Güncel Gönderiler: Araştırma Çıktıları | TR-Dizin | WoS | Scopus | PubMed
Toplam kayıt 13597, listelenen: 701-720
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Antimicrobial, anticholinesterase evaluation and chemical characterization of essential oil Phlomis kurdica Rech. fil. Growing in Turkey
(Taylor & Francis Inc, 2020)The Phlomis kurdica Rech.fil. (Lamiaceae) essential oil was investigated for its chemical constituents and in vitro biological activities. Volatile components were characterized, antimicrobial and anticholinesterase ... -
Synthesis and docking study of benzimidazole-triazolothiadiazine hybrids as aromatase inhibitors
(Wiley-V C H Verlag Gmbh, 2020)Aromatase is involved in the biosynthesis of estrogen and thus is a critical target for breast cancer. in this study, to identify new aromatase enzyme inhibitors, seven 3-[4-(5-methyl-1H-benzo[d]imidazol-2-yl)phenyl]-6-( ... -
Physicochemical characterization and pharmacokinetic evaluation of rosuvastatin calcium incorporated solid lipid nanoparticles
(Elsevier, 2020)Rosuvastatin calcium (RCa) is a very efficient antihyperlipidemic agent, however, being a BCS class II drug, results in poor oral bioavailability. the present study focused on the enhancement of oral bioavailability of RCa ... -
A novel lanthanide-chelate based molecularly imprinted cryogel for purification of hemoglobin from blood serum: An alternative method for thalassemia diagnosis
(Elsevier Sci Ltd, 2020)Purification and analyzing of proteins is an essential means for understanding their function and diseases associated with their lack or defect. in this research, a new lanthanide-chelate based molecularly imprinted polymer ... -
Carbonic anhydrase, obstructive sleep apnea and hypertension: Effects of intervention
(Wiley, 2020)Whole blood carbonic anhydrase activity (CAa) is increased in patients with obstructive sleep apnea (OSA). Our study investigated the influence of positive airway pressure (PAP) or CA inhibitor acetazolamide (ACT) therapy ... -
Calcium channel blockers: molecular docking and inhibition studies on carbonic anhydrase I and II isoenzymes
(Taylor & Francis Inc, 9999)Carbonic anhydrases (CAs) are potent dehydration of carbonic acid and catalyst of the reversible hydration of carbon dioxide. Here, CA I and CA II was purified from human erythrocytes using the simple chromatographic method ... -
Synthesis of some novel 3,4,5-trisubstituted triazole derivatives bearing quinoline ring and evaluation of their antimicrobial activity
(Taylor & Francis Ltd, 9999)Some new 3,4,5-trisubstituted 1,2,4-triazole derivatives were synthesized and studied for their antimicrobial activity. the lead compounds were obtained starting from 8-hydroxyquinoline and ethyl 2-chloroacetate. the ... -
Multifunctional quinoxaline-hydrazone derivatives with acetylcholinesterase and monoamine oxidases inhibitory activities as potential agents against Alzheimer's disease
(Springer Birkhauser, 2020)Multitarget molecules are considered as an effective way for the treatment of AD, instead of the classic one-drug-one-target strategy because of the multifactorial nature of AD. A variety of studies indicate that several ... -
Economic growth and environmental degradation: evidence from the US case environmental Kuznets curve hypothesis with application of decomposition
(Routledge Journals, Taylor & Francis Ltd, 9999)This study re-tests the environmetal Kuznets curve (EKC) hypothesis for the US, based on a methodology that differentiates this study from previous empirical studies.To this aim, the per-capita income series (variable) is ... -
Development of emergent literacy skills of a child with hearing loss: a longitudinal case study
(Routledge Journals, Taylor & Francis Ltd, 9999)This longitudinal case study aimed to investigate the development of emergent literacy skills of a child with hearing loss was carried out in a research and application centre which provides full-time day education using ... -
Sulfonamides incorporating ketene N,S-acetal bioisosteres as potent carbonic anhydrase and acetylcholinesterase inhibitors
(Wiley-V C H Verlag Gmbh, 2020)In this study, 15 novel compounds in a series of sulfonamide-based ketenes (7a-o) were synthesized and characterized using Fourier-transform infrared spectroscopy, nuclear magnetic resonance spectroscopy, and mass spectrometry. ... -
Effect of different molecular weight PLGA on flurbiprofen nanoparticles: formulation, characterization, cytotoxicity, and in vivo anti-inflammatory effect by using HET-CAM assay
(Taylor & Francis Ltd, 2020)Objective: the effect of polymers used in nanoparticle (NP) production on the formulation properties is one of the few studied issues. Therefore, this study aims to formulate flurbiprofen (FLB) loaded NPs with different ... -
Screening of non-alkaloid acetylcholinesterase and carbonic anhydrase isoenzymes inhibitors of Leiotulus dasyanthus (K. Koch) Pimenov & Ostr. (Apiaceae)
(Taylor & Francis Inc, 2020)The oxidant, cholinesterase, and carbonic anhydrase inhibitions of essential oils and their major compounds of Leiotulus dasyanthus and molecular docking studies of alpha-pinene and (TM)-3-carene were evaluated in this ... -
The prediction of personality, culture and coping strategies on university students' psychological help seeking attitudes
(Mehmet Tekerek, 2020)This study has attempted to investigate the predictability of university students' personality traits, cultural values, stress coping strategies, negative automatic thoughts and gender on their professional/formal psychological ... -
Synthesis, Docking Studies and Biological Activity of New Benzimidazole- Triazolothiadiazine Derivatives as Aromatase Inhibitor
(Mdpi, 2020)In the last step of estrogen biosynthesis, aromatase enzyme catalyzes the conversion of androgens to estrogens. Aromatase inhibition is an important way to control estrogen-related diseases and estrogen levels. in this ... -
Potential Antioxidant and Enzyme Inhibitory Effects of Nanoliposomal Formulation Prepared from Salvia aramiensis Rech. f. Extract
(Mdpi, 2020)Salvia aramiensis Rech. f. is a species that grows only in Hatay, Turkey and is used as a traditional stomachic tea. Neither the chemical composition nor the potential bioactivity of the plant has been investigated before. ... -
Secondary metabolites from Verbascum bugulifolium Lam. and their bioactivities
(Taylor & Francis Ltd, 9999)Five iridoid glycosides catalpol (1), specioside (2), ajugol (3), ajugoside (4), 8-O-acetylharpagide (5), two phenylethanoid glycosides, verbascoside (6) and glucopyranosyl-(1 -> G(i)-6)-martynoside (7), four flavonoids, ... -
EVALUATION OF ANTICANDIDAL EFFECTS OF ESSENTIAL OILS OF COMMERCIAL LAVENDER (Lavandula angustifolia Miller) IN COMBINATION WITH KETOCONAZOLE AGAINTS SOME Candida Berkhout STRAINS
(Trakya Univ Balkan Yerlesesi Enstituler Binasi, 2020)Application of combination studies with essential oils and standard antifungal drugs may reduce adverse effects of synthetic drugs and serve as alternative approach against various pathologies including candidiasis. the ... -
Fleet modelling in strategic multi-criteria decision-making of approved training organization from capacity building and resource dependency theory perspective: risk taxonomy methodology
(Emerald Group Publishing Ltd, 2020)Purpose in this study, research problem has been designed as a fleet-based optimization problem. This paper aims to present fleet modelling with risk taxonomy. Fleet modelling has been assumed as strategic multi-criteria ... -
Chemical Composition of Volatile Oils of Fresh and Air-Dried Buds of Cannabis chemovars, Their Insecticidal and Repellent Activities
(Sage Publications Inc, 2020)The volatile oils of fresh and air-dried buds of 3 different varieties of Cannabis, namely, high cannabidiol (CBD) chemotype, inter- mediate CBD/tetrahydrocannabinol chemotype, and high THC chemotype were prepared by ...
