TR-Dizin İndeksli Yayınlar Koleksiyonu by Institution Author "Yurttaş, Leyla"
Now showing items 1-4 of 4
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Synthesis and evaluation of novel 2-[(1,2,4-triazol-3-yl)thio]acetamide derivatives as potential serum paraoxonase-1 (PON1) activators
Yurttaş, Leyla; Küçükoğlu, Kaan; Nadaroğlu, Hayrunnisa; Kaplancıklı, Zafer Asım (Marmara University, Fac Pharmacy, 2017)Coronary artery disease and low-density lipoprotein (LDL) levels in the blood have long been known to be associated with peripheral vascular diseases. Paraoxonase-1 (PON1) enzyme is related to serum levels of high-density ... -
Synthesis of novel thiazolylpyrazoline derivatives and evaluation of theirantimicrobial activities and cytotoxicities
Tabbı, Aouatef; Kaplancıklı, Zafer Asım; Tebbanı, Dahmane; Yurttaş, Leyla; Cantürk, Zerrin; Atlı Eklioğlu, Özlem; Turan, Gülhan (2016)Several novel thiazolylpyrazoline derivatives were synthesized by reacting substituted 3,5-diaryl-1-thiocarba-moyl-2-pyrazolines with phenacylbromides. The structures of the synthesized compounds were con rmed by IR,1HNMR,13C ... -
Synthesis, anticandidal activity, and cytotoxicity of some thiazole derivatives with dithiocarbamate side chains
Yurttaş, Leyla; Özkay, Yusuf; Demirci, Fatih; Göğer, Gamze; Yıldırım, Şafak Ulusoylar; Abu Mohsen, Usama; Kaplancıklı, Zafer Asım (Scientific Technical Research Council Turkey-Tubitak, 2014)Some thiazole derivatives bearing dithiocarbamic acid esters were synthesized in order to investigate their anticandidal activity and cytotoxicity. The structures of the obtained final compounds (6a-j) were confirmed by ... -
Yeni benzotiyazol türevlerinin A549 akciğer karsinomu hücre hattına karşı antikanser etkinliğinin ilk basamak araştırması
Amaç: Bu çalışmada, benzotiyazol-2-amin kalıntısının bilinen antiproliferatif özelliklerinden yola çıkılarak yeni kemoterapötik ajanların sentezlenmesi amaçlanmıştır. Yeni sentezlenen bileşiklerin antitümör etkinliği, A549 ...
