Kurum Yazarı "Seller, Zerrin" WoS İndeksli Yayınlar Koleksiyonu İçin Listeleme
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Inhibition of DNA synthesis by carvacrol in mouse myoblast cells bearing a human N-RAS oncogene
Sivas, Hülya; Seller, Zerrin; Başer, K. Hüsnü Can (Urban & Fischer Verlag, 2003)Monoterpenes are dietary components found in the essential oils of a wide variety of plants. A number of these monoterpenes have antitumor activity. We have investigated the effects of carvacrol obtained by fractional ... -
Modification of intracellular free calcium in cultured F2408 embryo fibroblasts by 3-sub substituted-2-thiohydantoin derivatives
Seller, Zerrin; Benkli, Kadriye; Akalın, G; Kaplancıklı, Zafer Asım (Wiley, 2004)3-substituted-2-thiohydantoin derivatives were synthesized and their Structures elucidated by IR, H-1-NMR spectroscopy and elemental analysis. The cytotoxicity of the 2-thiohydantoin derivatives to rat embryo fibroblasts ... -
Preperation and in vitro characterization of epsilon-viniferine and vincristine sulfate loaded PLGA-b-PEG nanoparticles
Öğünç Keçeci, Yüksel; Demirel, Müzeyyen; Yakar, Arzu; Seller, Zerrin (Lippincott Williams & Wilkins, 2015)… -
Synthesis and Evaluation of New Dithiocarbamic Acid 6,11-Dioxo-6,11-dihydro-1H-anthra[1,2-d]-imidazol-2-yl Methyl Esters
Önder, Nur İpek; Seller, Zerrin; Özkay, Yusuf (Wiley-V C H Verlag GMBH, 2015)A novel series of dithiocarbamic acid 6,11-dioxo-6,11-dihydro-1H-anthra[1,2-d]imidazol-2-yl methyl esters were synthesized and their cytotoxic and apoptotic activities were evaluated on HeLa cells. Some of these compounds ... -
Synthesis of 2-substituted-N-[4-(1-methyl-4,5-diphenyl-1H-imidazole-2-yl) phenyl]acetamide derivatives and evaluation of their anticancer activity
Özkay, Yusuf; Işıkdağ, İlhan; Seller, Zerrin; Akalın Çiftçi, Gülsen (Elsevier France-Editions Scientifiques Medicales Elsevier, 2010)In the present study 18 novel imidazole-(benz)azole and imidazole-piperazine derivatives were synthesized in order to investigate their probable anticancer activity. The structures of the compounds were confirmed by IR, ... -
Synthesis of some 2,4-di- and 2,3,4-trisubstituted benzimidazo[1,2-a]pyrimidines and evaluation of their cytotoxicities towards F2408 and 5RP7 cells
Meriç, Asiye; Seller, Zerrin; Karayel, Arzu; Özbey, Süheyla (Chiminform Data S A, 2006)This article describes the synthesis of 2,4-di- and 2,3,4-trisubstituted benzimidazo[1,2-alpyrimidine derivatives which were tested for their cytotoxicities and their spectral characterizations by IR, H-1- and C-13-NMR, ... -
Synthesis of some 3,4-disubstituted-6,7-dihydro-imidazo[2,1-b][1,3]thiazole and 3,4-disubstituted-7,8-dihydro-6H-imidazo[2,1-b][1,3]thiazine derivatives and evaluation of their cytotoxicities against F2408 and 5RP7 cells
Meriç, Asiye; Seller, Zerrin; Hatipoğlu, İbrahim (Birkhauser Boston Inc, 2008)This article describes the synthesis of 3,4-disubstituted-6,7-dihydro-imidazo[2,1-b][1,3]thiazoles and 3,4-disubstituted-7,8-dihydro-6H-imidazo[2,1-b][1,3]thiazines, having substituted or nonsubstituted phenyl rings at the ... -
Synthesis, characterization of some transition-metal complexes of a new heptadentate N(5)S(2) Schiff-base ligand and the effects of these metal complexes on U2OS cells cytotoxicity and DNA cleavage activity
Uluçam, G.; Beynek, Nesrin; Seller, Zerrin; Akalın Çiftçi, Gülsen; Turan, Gülhan; Benkli, Kadriye (Taylor & Francis LTD, 2008)Metal complexes of a heptadentate N(5)S(2) donor Schiff-base ligand were synthesized by the template reaction between 2,6-bis(2-aminothiophenoxymethyl)pyridine and 2,2 '-bipyridine-6,6'-dicarboxaldehyde in the presence of ... -
Towards Novel Anti-tumor Strategies for Hepatic Cancer: epsilon-Viniferin in Combination with Vincristine Displays Pharmacodynamic Synergy at Lower Doses in HepG2 Cells
Özdemir, Filiz; Akalın Çiftçi, Gülsen; Sen, Mesut; Önder, Nur İpek; İşcan, Arzu; Kutlu, Hatice Mehtap; Seller, Zerrin (Mary Ann Liebert, Inc, 2014)Hepatocellular carcinoma is the fifth most common cancer and the third leading cause of cancer-related deaths worldwide. The efficacy of novel combination treatments are increasingly evaluated with use of integrative biology ... -
Ultrastructural Examination of Intracellular Calcium Changes in Ovarian Cancer
Ayrım, Aysun; Dağ, İlknur; Seller, Zerrin (Parlar Scientific Publications (PSP), 2017)In this study, following the fibronectin-coated integrin activation in ovarian cancer cells (SKOV-3), endoplasmic reticulum (ER) stress was generated by intracellular calcium increase and then possible apoptotic effects ... -
Vincristine and epsilon-viniferine-loaded PLGA-b-PEG nanoparticles: pharmaceutical characteristics, cellular uptake and cytotoxicity
Ogunc, Yüksel; Demirel, Müzeyyen; Yakar, Arzu; Seller, Zerrin (Taylor & Francis LTD, 2017)The objective of this study was to prepare the epsilon-viniferine and vincristine-loaded PLGA-b-PEG nanoparticle and to investigate advantages of these formulations on the cytotoxicity of HepG2 cells. Prepared nanoparticle ...