Yazar "Turan, Gülhan" için WoS İndeksli Yayınlar Koleksiyonu listeleme
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Synthesis and Evaluation of Thiazole - Pyrimidine Derivatives as New Anticandidal and Cytotoxic Agents
Turan, Gülhan; Altıntop, Mehlika Dilek; Kaplancıklı, Zafer Asım; Özdemir, Ahmet; Demirci, Fatih; Ilgın, Sinem; Göğer, Gamze (Springer, 2014)The aim of this study was to describe the synthesis of four new 2-(3,4-diphenyl-3H-thiazol-2-ylidene)amino-4,6-dimethylpyrimidine derivatives, which were screened for their anticandidal activity and cytotoxicity. The title ... -
Synthesis and in Vitro Evaluation of New Nitro-Substituted Thiazolyl Hydrazone Derivatives as Anticandidal and Anticancer Agents
Altıntop, Mehlika Dilek; Özdemir, Ahmet; Turan, Gülhan; Ilgın, Sinem; Atlı Eklioğlu, Özlem; Demirci, Fatih; Kaplancıklı, Zafer Asım (MDPI AG, 2014)Fourteen new thiazolyl hydrazone derivatives were synthesized and evaluated for their anticandidal activity using a broth microdilution assay. Among the synthesized compounds, 2-[2-((5-(4-chloro-2-nitrophenyl) furan-2-yl) ... -
Synthesis and In Vitro Evaluation of Some Hydrazone Derivatives as Potential Antibacterial Agents
Kaplancıklı, Zafer Asım; Altıntop, Mehlika Dilek; Özdemir, Ahmet; Turan, Gülhan; Göğer, Gamze; Demirci, Fatih (Bentham Science Publ LTD, 2014)Nineteen N'-(benzylidene)-2-[(pyrimidin-2-yl)thio]acetohydrazides were obtained via the nucleophilic addition-elimination reaction of 2-[(pyrimidin-2-yl)thio)]acetohydrazide with aromatic aldehydes. The synthesized compounds ... -
Synthesis and study of antibacterial and antifungal activities of novel 2-[[(benzoxazole/benzimidazole-2-yl)sulfanyl] acetylamino]thiazoles
Kaplancıklı, Zafer Asım; Turan, Gülhan; Revial, G; Güven, Kıymet (Pharmaceutical Soc Korea, 2004)Several 2-[[(benzoxazole/benzimidazole-2-yl)sulfanyl]acetylamino]thiazoles derivatives were synthesized by reacting 4-substituted-2-(chloroacetylamino)thiazoles with benzoxazole/benzimidazole-2-thioles in acetone and in ... -
Synthesis and the selective antifungal activity of 5,6,7,8-tetrahydroimidazo[1,2-a]pyridine derivatives
Özdemir, Ahmet; Turan, Gülhan; Kaplancıklı, Zafer Asım; İşcan, Gökalp; Khan, Shabana I.; Demirci, Fatih (Elsevier France-Editions Scientifiques Medicales Elsevier, 2010)Even though there are new classes of compounds now frequently used in treatment of fungal infections, the density of deeply invasive candidiasis has increased at least 10-fold during the past decade. Furthermore, many ... -
Synthesis of 1-acetyl-3-(2-thienyl)-5-aryl-2-pyrazoline derivatives and evaluation of their anticancer activity
Özdemir, Ahmet; Altıntop, Mehlika Dilek; Kaplancıklı, Zafer Asım; Turan, Gülhan; Çiftçi, Gülsen Akalın; Yıldırım, Şafak Ulusoylar (Informa Healthcare, 2013)In the present study, 1-acetyl-3-(2-thienyl)-5-aryl-2-pyrazoline derivatives (1-6) were synthesized via the ring closure reaction of 1-(2-thienyl)-3-aryl-2-propen-1-ones with hydrazine hydrate in acetic acid. The chemical ... -
Synthesis of novel thiazolylpyrazoline derivatives and evaluation of their antimicrobial activities and cytotoxicities
Tabbi, Aouatef; Kaplancıklı, Zafer Asım; Tebbani, Dahmane; Yurttaş, Leyla; Cantürk, Zerrin; Atlı Eklioğlu, Özlem; Turan, Gülhan (Scientific Technical Research Council Turkey-Tubitak, 2016)Several novel thiazolylpyrazoline derivatives were synthesized by reacting substituted 3,5-diaryl-1-thiocarbamoyl-2-pyrazolines with phenacylbromides. The structures of the synthesized compounds were confirmed by IR, H-1 ... -
Synthesis of some 1-[(N,N-disubstituted thiocarbamoylthio)acetyl]-3-(2-thienyl)-5-aryl-2-pyrazoline derivatives and investigation of their antibacterial and antifungal activities
Turan, Gülhan; Özdemir, Ahmet; Güven, Kıymet (Wiley-V C H Verlag GMBH, 2005)Fourteen new 1-[(N,N-disubstituted thiocarbamoylthio)acetyl]-3-(2-thienyl)-5-aryl-2-pyrazoline derivatives (7a-n) were synthesised by reacting 1-(chloroacetyl)-3-(2-thienyl)-5-aryl-2-pyrazolines (5a-g) and appropriate ... -
Synthesis of some 2-[(benzazole-2-yl)thioacetylamino]thiazole derivatives and their antimicrobial activity and toxicity
Turan, Gülhan; Demirayak, Ezgi; Özdemir, Ahmet; Kaplancıklı, Zafer Asım; Yıldız, MT (Elsevier France-Editions Scientifiques Medicales Elsevier, 2004)Some 2-[(benzazole-2-yl)thioacetylamino]thiazole derivatives (III) were synthesized by reacting 4-methyl-2-(chloroacetylamino)thiazole derivatives (I) with benzazol-2-thiole (II) in acetone in the presence of K2CO3. The ... -
Synthesis of some 2-[(benzazole-2-yl)thioidiphenylmethylacetamide derivatives and their antimicrobial activity
Turan, Gülhan; Kaplancıklı, Zafer Asım; Uçucu, U; Özdemir, Ahmet; Chevallet, P; Tunalı, Yağmur (Taylor & Francis LTD, 2004)Some 2-[(benzazole-2-yl)thio]diphenylmethylacetamide derivatives were synthesized by reacting 2-chloroacethylaminodiphenylmethane with benzazole-2-thions. The structure elucidation of the compounds was performed by IR, 1H ... -
Synthesis of some 4-arylidenamino-4H-1,2,4-triazole-3-thiols and their antituberculosis activity
Özdemir, Ahmet; Turan, Gülhan; Kaplancıklı, Zafer Asım; Chevallet, Pierre (Taylor & Francis LTD, 2007)The increasing clinical importance of drug-resistant mycobacterial pathogens has lent additional urgency to microbiological research and new antimycobacterial compound development. For this purpose, new triazoles were ... -
Synthesis of Some Benzofuran and Their Antituberculosis Activity
Turan, Gülhan; Özdemir, Ahmet; Kaplancıklı, Zafer Asım; Altıntop, Mehlika Dilek (Elsevier Science BV, 2011)… -
Synthesis of Some Benzothiazole Based Piperazine-Dithiocarbamate Derivatives and Evaluation of Their Anticancer Activities
Turan, Gülhan; Özkay, Yusuf; Özdemir, Ahmet; Kaplancıklı, Zafer Asım; Altıntop, Mehlika Dilek (Bentham Science Publ LTD, 2011)Some benzothiazole derivatives bearing piperazine and dithiocarbamate moieties were synthesized in order to investigate their anticancer activity. The structures of the obtained compounds were confirmed by spectral data ... -
Synthesis of some dithiocarbamate derivatives and their antimicrobial activity
Kaplancıklı, Zafer Asım; Turan, Gülhan; Revial, G; İşcan, Gökalp (Taylor & Francis LTD, 2004)Some new, 2-[(N-substituted aminothiocarbonylthio)acetyl]aminothiazole, N-substituted aminothiocarbonylthioacetylaminodiphenylmethane and 9-[(N-substituted aminothiocarbonylthio)acetyl]aminofluorene derivatives were ... -
Synthesis of Some Imidazo[1,2-a]pyrazine Derivatives and Evaluation of Their Antinociceptive Activity
Turan, Gülhan; Yurttaş, Leyla; Özdemir, Ahmet; Kaplancıklı, Zafer Asım; Masquefa, Carine (Aves Press LTD, 2016)Objective: The imidazopyrazine ring is a biologically active heterocyclic ring. Many hydrazide-hydrazone-possessing compounds have been reported to have interesting bioactivity, such as antibacterial, antifungal, anticonvulsant, ... -
The synthesis of some new hydrazone derivatives containing the benzothiazole moiety
Özdemir, Ahmet; Turan, Gülhan; Kaplancıklı, Zafer Asım; Altıntop, Mehlika Dilek (Serbian Chemical Soc, 2012)Hydrazones are an important class of compounds found in many synthetic. products. Due to their importance in synthetic chemistry, the present article reports the synthesis of a new series of ten compounds based on the ... -
Synthesis of Some Novel Triazole Derivatives and Investigation of Their Antimicrobial Activities
Altıntop, Mehlika Dilek; Kaplancıklı, Zafer Asım; Turan, Gülhan; Özdemir, Ahmet; Demirci, Fatih; İşcan, Gökalp; Revial, Gilbert (Taylor & Francis Inc, 2011)[image omitted] The aim of this study is to synthesize new triazole derivatives and investigate their antimicrobial activities. 4-Amino-5-(2-cyclohexylethyl)-3-[N-(benzothiazole-2-yl)acetamido]thio-4H-1,2,4-triazole and ... -
Synthesis of Some Thiadiazole Derivatives as New Anticonvulsant Agents
Kaplancıklı, Zafer Asım; Altıntop, Mehlika Dilek; Özdemir, Ahmet; Turan, Gülhan; Can, Özgür Devrim (Elsevier Science BV, 2011)… -
Synthesis of some thiazolyl-pyrazoline derivatives and preliminary investigation of their hypotensive activity
Turan, Gülhan; Chevallet, P; Kılıç, FS; Erol, Kevser (Editions Scientifiques Medicales Elsevier, 2000)Some 1-(4-arylthiazol-2-yl)-3,5-diaryl-2-pyrazoline derivatives were synthesized by reacting 1-thiocarbamoyl-3,5-diaryl-2-pyrazoline derivatives with phenacetylbromide in ethanol. The structural elucidation of the compounds ... -
Synthesis of some triazolyl-antipyrine derivatives and investigation of analgesic activity
Turan, Gülhan; Sivaci, M; Kılıç, FS; Erol, K (Elsevier France-Editions Scientifiques Medicales Elsevier, 2001)The synthesis of some triazolyl-antipyrine derivatives starting from 4-chloroacetamidoantipyrine and 3-(aryloxyalkyl)-4-ethyl/phenyl-5-mercapto-1,2,4-triazoles is described. The chemical structures of the compounds were ...