Kurum Yazarı "Seller, Zerrin" WoS İndeksli Yayınlar Koleksiyonu İçin Listeleme
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Alterations in Mrna Expression of Apoptosis-Related Genes After Treatment of Skov-3 Cells With Cardamonin
Sarı Kılıçaslan, Seda Mehtap; Ogunc, Yüksel; Apaydın, Elif; Seller, Zerrin (Parlar Scientific Publications (PSP), 2018)The aim of this study is to investigate the effect of cardamonin on mRNA expression of apoptosis-related genes and proliferation after treatment of ovarian epithelial cells, SKOV-3. Real time cellular assay and acridine ... -
Anticancer Activity of Some Bisbenzimidazoles
Işıkdağ, İlhan; Özkay, Yusuf; İncesu, Zerrin; Akalın Çiftçi, Gülsen (Verlag Z Naturforsch, 2011)The discovery of DNA topoisomerases has added a new dimension to the study of anticancer drugs. Bishenzimidazole derivatives are important compounds known as DNA topoisomerase 1 inhibitors. In the present study, some ... -
Antimicrobial and anticancer effects of some 2-(substitutedsulfanyl)-N-(5-methyl-isoxazol-3-yl)acetamide derivatives
Özkay, Yusuf; Seller, Zerrin; Önder, Nur İpek; Tunalı, Yağmur; Karaca Gencer, Hülya; Işıkdağ, İlhan; Uçucu, Ümit (Springer Birkhauser, 2013)In the present study, some isoxazole-(benz)azole derivatives (3a-3j) were synthesized by considering antimicrobial and anticancer potencies of azole compounds. Chemical structures of obtained compounds (3a-3j) were confirmed ... -
The antimutagenic and antimitotic properties of the extract of the lichen Cetraria aculeata
Sivas, Hülya; Seller, Zerrin; Tüylü, Berrin; Türk, A; Barutca, B (Academic Press Inc Elsevier Science, 2004)… -
Antiproliferative effects of some N-benzylideneanilines
Özkay, Yusuf; Seller, Zerrin; Işıkdağ, İlhan; Yesilkaya, Mehmet (John Wiley & Sons LTD, 2008)A series of Schiff bases including N-benzylideneaniline (NBA) nuclei were prepared. The chemical products obtained were characterized by mass spectometry (APCI), H-1 NMR, and IR spectroscopy in order to seek their cytotoxic ... -
Apoptotic effects of epsilon-viniferin in combination with cis-platin in C6 cells
Özdemir, Filiz; Apaydın, Elif; Önder, Nur İpek; Şen, Mesut; Ayrim, Aysun; Öğünç Keçeci, Yüksel; Seller, Zerrin (Springer, 2018)Glioblastoma (GBM) is one of the most common and lethal forms of primary brain tumors in human adults. Treatment options are limited, and in most cases ineffective. Natural products are sources of novel compounds endowed ... -
Apoptotic Effects of Some Thiohydantoin Derivatives
Seller, Zerrin; Akalın Çiftçi, Gülsen (Turkish Biochem Soc, 2010)Objectives: The aim of this study is to investigate the effects of newly synthesized 3-phenly-and 3-(4-methoxyphenyl)-2-thiohydantoin derivatives on 5RP7 ve CO25 cell apoptosis. Methods and Materials: Thiohydantoin derivatives ... -
Calcium Mobilization and Inhibition of Akt Reduced the Binding of PEO-1 Cells to Fibronectin
Sarı Kılıçaslan, Seda Mehtap; Ayrim, Aysun; Apaydın, Elif; Seller, Zerrin (Turkish Pharmacists Assoc, 2018)Objectives: To investigate the effects of intracellular calcium (Ca2+) mobilization, beta-catenin and Akt signal pathways after the binding of metastatic ovarian cells to fibronectin. Materials and Methods: The expression ... -
Combined Treatment of Cisplatin and Epsilon-Viniferin Induces C6 (Rat Glioma) Cell Apoptosis in Time-Dependent Manner
Apaydın, Elif; Ayrim, Aysun; Mert, Nur İpek Önder; Seller, Zerrin; Özdemir, Filiz (International Institute of Anticancer Research, 2014)… -
Cytotoxicity Screening, Antioxidant Activity and Phenolic Profile of Two Species of Thymus on Human Cervical and Ovarian Cancer Cells Lines in Vitro
Özdemir, Filiz; Küçük, Sevim; Göğer, Fatih; Seller, Zerrin (Parlar Scientific Publications (PSP), 2017)The aim of this study was to determine of cytotoxic, antioxidant activity and phenolic profile of the two species of Thymus which are Thymus sipyleus Boiss. and Thymus leucostomus Hausskn. et Velen. (endemic). For this ... -
Determination of Cytotoxic and Anticandidal Activities of Three Verbascum L. Species from Turkey: V-cheiranthifolium Boiss. var. asperulum (Boiss.) Murb. Monorg., V-pycnostachyum Boiss. & Heldr and V-orgyale Boiss. & Heldr
Küçük, Sevim; Özdemir, Filiz; İşcan, Gökalp; Seller, Zerrin (Turkish Pharmacists Assoc, 2016)Purpose of this study is to determine of cytotoxic and anticandidal activities of Verbascum cheiranthifolium Boiss. var. asperulum (Boiss.) Murb. Monorg., Verbascum pynostachyum Boiss. & Heldr and Verbascum orgyale Boiss. ... -
Determination of genotoxic, antigenotoxic and cytotoxic potential of the extract from lichen Cetraria aculeata (Schreb.) Fr. in vitro
Sivas, Hülya; Seller, Zerrin; Tüylü, Berrin; Türk, A. O.; Barutca, B. (Wiley, 2008)Naturally occurring compounds can have protective effects towards mutagens and carcinogens as shown by numerous studies. In the present study, the genotoxic/antigenotoxic activities of the extract from lichen Cetraria ... -
Determination of Phenolic Compounds, Cytotoxic, Antioxidant and Anticandidal Effects of Tribulus Terrestris L. (Zygophyllaceae)
Küçük, Sevim; Göğer, Fatih; İşcan, Gökalp; Özdemir, Filiz; Kırımer, Neşe; Seller, Zerrin (Parlar Scientific Publications (PSP), 2017)This study was investigated the potential cytotoxic, antioxidant and anticandidal activities of T terrestris in vitro. Both the fruit and aerial parts of the T terrestris extract showed a significant cytotoxic effects in ... -
Direct and protective effects of single or combined addition of vincristine and epsilon-viniferin on human HepG2 cellular oxidative stress markers in vitro
Tarhan, Seda; Özdemir, Filiz; Seller, Zerrin; Demirkan, Emine Sutken (Springer, 2016)The objective of this study is to examine the direct effects of low doses and high doses of epsilon-viniferin, a substance known to be an antioxidant, and vincristine sulphate, a chemotherapeutic agent, alone and in ... -
Effects of fibronectin and type IV collagen on osteosarcoma cell apoptosis
Seller, Zerrin; Hatipoğlu, İbrahim; Sivas, Hülya; Ergene, Emel; Çiftçi, Gülsen Akalın (Natl Inst Science Communication-Niscair, 2013)The aims of this study are the investigation of the effects of fibronectin and type IV collagen extracellular matrix proteins and the role of caspase-3 and -9 on cis-platin induced U2-OS apoptosis were studied. First the ... -
Effects on Caspases Activation By Using a Combination of Cis-Platin With E-Viniferin in Rat Glioma Cells
Mert, Nur İpek Önder; Sen, Mesut; Apaydın, Elif; Seller, Zerrin; Özdemir, Filiz (International Institute of Anticancer Research, 2014)…