Kurum Yazarı "Kutlu, Hatice Mehtap" Sağlık Yönetimi İçin Listeleme
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Ceranib-2 induces apoptosis in prostate cancer cells
Kuş, Gökhan; Kabadere, Selda; Kutlu, Hatice Mehtap; Uyar, Ruhi (Wiley-Blackwell, 2015)… -
Comparative Study on Induction of Apoptosis in A549 Human Lung Adenocarcinoma Cells by C2 Ceramide or Ceranib-2
Kuş, Gökhan; Kutlu, Hatice Mehtap; Vejselova, Djanan; Çömlekçi, Emre (Zoological Soc Pakistan, 2017)Investigation of ceramide and ceramidases on cancer therapy had become popular in recent years. Ceramide is a metabolite in sphingolipid pathway of the cells that has an ability to promote cell death in tumor cells when ... -
Induction of apoptosis in prostate cancer cells by the novel ceramidase inhibitor ceranib-2
Kuş, Gökhan; Kabadere, Selda; Uyar, Ruhi; Kutlu, Hatice Mehtap (Springer, 2015)Ceramidases are key enzymes that decrease ceramide levels in cells. A reduction in ceramide concentration impairs ceramide signalling, and results in apoptosis resistance in cancer cells. This study investigates the potential ...