Utilizing the Cross-Reactivity of MIPs
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Erişim
info:eu-repo/semantics/closedAccessTarih
2015Yazar
Yılmaz, EcevitBilling, Johan
Nilsson, Carina
Boyd, Brian
Keçili, Rüstem
Nivhede, David
Rees, Anthony
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The crossreactivity of molecularly imprinted polymers (MIPs) and its practical implications are discussed. Screening of MIP libraries is presented as a fasttrack route to discovery of resins selective towards new targets, exploiting the fact that MIPs imprinted with one type of template molecule also show recognition to related and sometimes also to apparently unrelated molecules. Several examples from our own and others' studies are presented that illustrate this crossreactivity and the pattern of recognition is discussed for selected examples.