Erişim şekli için "info:eu-repo/semantics/openAccess" Analitik Kimya Anabilim Dalı listeleme
Toplam kayıt 15, listelenen: 1-15
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Analysis of anticancer drugs using thin layer chromatography- A review
(Marmara University, 2018)Cancer is a fatal disease and cancer incidence is increasing from day to day. Thus, anticancer drugs are widely used and their analysis requires simple and effective analytical procedures. Thin layer chromatography (TLC) ... -
The determination of bupropion hydrochloride in pharmaceutical dosage forms by original UV - and second derivative UV spectrophotometry, potentiometric
(2010)Bupropion hidroklorür'ün (BUP) farmasötik tabletlerindeki tayini için spektrofotometrik, potansiyometrik ve kondüktometrik yöntemler geliştirilmiştir, ilk yöntem olan orjinal UV-spektrofotometri yöntemi için optimal dalgaboyu ... -
Determination of Bupropion Using Liquid Chromatography with Fluorescence Detection in Pharmaceutical Preparations, Human Plasma and Human Urine
(Oxford University Press Inc, 2012)A novel pre-column derivatization reversed-phase high-performance liquid chromatography with fluorescence detection is described for the determination of bupropion in pharmaceutical preparation, human plasma and human urine ... -
Development and Validation of a New HPLC Method for the Determination of Quetiapine and Its Metabolites 7- Hydroxy Quetiapine and Quetiapine Sulfoxide in Rat Plasma
(2016)Sıçan plazmasında ketiapin ve metabolitleri 7-hidroksi ketiapin ve ketiapin sülfoksit'in tayini için yeni bir yüksek performanslı sıvı kromatografisi yöntemi geliştirilmiş ve valide edilmiştir. Ayrım, C18 kolon (Zorbax ... -
Development of a validated high-performance liquid chromatographic method for the determination of Lurasidone in pharmaceuticals
(Marmara University, Fac Pharmacy, 2017)A new, rapid and simple HPLC method for determination of Lurasidone in its tablets has been developed and validated. Lurasidone and internal standard (Chlorpromazine) was separated on a Zorbax XDB C8 column (4.6 x 50 mm, ... -
Development of a validated HPLC method for simultaneous determination of olanzapine and aripiprazole in human plasma
(Marmara University, 2018)A simple and rapid HPLC method was developed and validated for simultaneous determination of two antipsychotic drugs, olanzapine and aripiprazole, in spiked human plasma. Optimization studies were performed using experimental ... -
Development of Validated and Stability-Indicating LC-DAD and LC-MS/MS Methods for Determination of Avanafil in Pharmaceutical Preparations and Identification of a Novel Degradation Product by LCMS-IT-TOF
(MDPI, 2018)Avanafil (AVA), one of the most effective drugs prescribed for erectile dysfunction, is a pyrimidine-derivative PDE5 inhibitor. In the current work, new LC methods were developed and validated for quantitative determination ... -
Pharmacological and Toxicological Screening of Novel Benzimidazole-Morpholine Derivatives as Dual-Acting Inhibitors
(MDPI, 2017)The aim of this study was to investigate acetylcholinesterase (AChE), monoamine oxidase A (MAO-A), monoamine oxidase B (MAO-B), cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2) enzyme inhibitory, and antimicrobial ... -
A Rapid Determination of Patulin Using Capillary Zone Electrophoresis and its Application to Analysis of Apple Juices
(Oxford University Press Inc, 2013)This study describes a capillary zone electrophoretic method for the determination of patulin. An optimum run buffer was found to be 25 mM of sodium tetraborate and 10% acetonitrile (v/v) at pH 10. Optimum conditions were ... -
A Sensitive and Rapid Determination of Ranitidine in Human Plasma by HPLC with Fluorescence Detection and its Application for a Pharmacokinetic Study
(Oxford University Press Inc, 2012)… -
Simple method of paroxetine determination using a single channel FIA with no in-line reaction process
(Japan Soc Analytical Chemistry, 2003)A flow-injection analysis (FIA) of paroxetine hydrochloride (PRX), a selective serotonin reuptake inhibitor (SSRI) currently used as an antidepressant drug, is described. A 0.1 mol dm(-3) acetate buffer at pH 3.07 was found ... -
A Stability Indicating Ion-Pair Lc Method for the Determination of Asenapine in Pharmaceuticals
(Soc Chilena Quimica, 2017)In this study, a new, simple and specific stability indicating ion-pair LC method was developed and fully validated for the determination of asenapine in tablets. The analysis was performed on an Agilent Eclipse XDB-C8 ... -
Synthesis of New Hydrazone Derivatives for MAO Enzymes Inhibitory Activity
(MDPI, 2017)In the present work, 14 new 1-substituted-2-phenylhydrazone derivatives were synthesized to evaluate their inhibitory activity against hMAO enzymes. The structures of the newly synthesized hydrazones 2a-2n were characterized ... -
Synthesis, Molecular Docking Studies, and Antifungal Activity Evaluation of New Benzimidazole-Triazoles as Potential Lanosterol 14 alpha-Demethylase Inhibitors
(Hindawi LTD, 2017)Due to anticandidal importance of azole compounds, a new series of benzimidazole-triazole derivatives(5a-5s) were designed and synthesized as ergosterol inhibitors. Thechemical structures of the target compounds were ... -
Validated Method for the Determination of Piroxicam by Capillary Zone Electrophoresis and Its Application to Tablets
(Hindawi Publishing Corporation, 2014)Simple and rapid capillary zone electrophoretic method was developed and validated in this study for the determination of piroxicam in tablets. The separation of piroxicam was conducted in a fused-silica capillary by using ...