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Toplam kayıt 18, listelenen: 1-10
Gadolinium-based contrast agents: in vitro paraoxonase 1 inhibition, in silico studies
(Taylor & Francis LTD, 2019)
Medications show their biological effects by interaction with enzymes, which have been known to play an essential role in the pathogenesis of many diseases. Inhibition or induction of drug metabolizing enzymes has an ...
Inhibition behaviours of some phenolic acids on rat kidney aldose reductase enzyme: an in vitro study
(Taylor & Francis LTD, 2017)
Aldose reductase (AR) inhibitors have vital importance in the treatment and prevention of diabetic complications. In this study, rat kidney AR was purified 19.34-fold with a yield of 3.49% and a specific activity of 0.88 ...
Inhibition effects of quinones on aldose reductase: Antidiabetic properties
(Elsevier, 2019)
Diabetes mellitus is a chronic metabolic disease characterized by abnormal glucose metabolism. Aldose reductase (AR) is the first enzyme in the polyol pathway and converts glucose to sorbitol. It plays a vital role as a ...
Anti-diabetic Properties of Calcium Channel Blockers: Inhibition Effects on Aldose Reductase Enzyme Activity
(Springer, 2019)
Aldose reductase (AR) belongs to NADPH-dependent oxidoreductases and converts glucose to sorbitol in the polyol pathway. AR inhibition is essential to prevent diabetic complications. Here, AR was purified from sheep kidney ...
Inhibition effects of pesticides on glutathione-S-transferase enzyme activity of Van Lake fish liver
(Wiley, 2018)
Glutathione-S-transferases (GSTs) have a function in xenobiotic metabolism. They are a significant multifunctional family with a wide variety of catalytic activities. In the current study, we determined in vitro inhibition ...
Evaluation of chalcones as inhibitors of glutathione S-transferase
(Wiley, 2018)
Glutathione S-transferases (GSTs) are the superfamily of multifunctional detoxification isoenzymes and play an important role in cellular signaling. In the present study, potential inhibition effects of chalcones were ...
The effects of some cephalosporins on acetylcholinesterase and glutathione S-transferase: an in vivo and in vitro study
(Taylor & Francis LTD, 2019)
Background: Glutathione S-transferase (GST) and acetylcholinesterase (AChE) are important enzymes in the metabolism. GSTs are primarily available in phase II metabolism. AChE is vital for neurodegenerative disorders. ...
Purification of Glucose 6-Phosphate Dehydrogenase From Gilthead Sea Bream (Sparus Aurata) Gill and Liver Tissues and Inhibition Effects of Some Metal Ions on Enzyme Activity
(Parlar Scientific Publications (PSP), 2017)
Fish is one of the most valuable protein sources and vulnerable to all environmental pollution including metals. Metals play vital roles in enzyme activities and other metabolic events with their bioaccumulative and ...
Phenolic compounds: The inhibition effect on polyol pathway enzymes
(Elsevier Ireland LTD, 2017)
The polyol pathway called as sorbitol way is a small part of glycose metabolism. The pathway is regarded as an important element in the pathogenesis of various diabetic complications in individuals with diabetes mellitus. ...
The interactions of cephalosporins on polyol pathway enzymes from sheep kidney
(Taylor & Francis LTD, 2018)
Context: Cephalosporins are derived from the fungus Acremonium. Due to their strong bactericidal ability, these drugs have to a wide usage in medicine.Objective: An investigation of the effects on sheep renal aldose reductase ...