Kurum Yazarı "Kaplancıklı, Zafer Asım" Makale Koleksiyonu İçin Listeleme
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Apoptotic effects of some carbazole derivatives on lung carcinoma and glioma cell lines
Çiftçi, Gülsen Akalın; Temel, Halide Edip; Yıldırım, Şafak Ulusoylar; Kaplancıklı, Zafer Asım; Altıntop, Mehlika Dilek; Genç, Lütfi (Springer Birkhauser, 2013)In this study, we aimed to study the apoptotic effects of 2-[(9-ethyl-9H-carbazol-3-yl)amino]-2-oxoethyl N,N-disubstituted dithiocarbamates on A549 lung carcinoma and C6 glioma cell lines. Cytotoxicity analyses of DNA ... -
Cytotoxic, Apoptotic and DNA Synthesis Inhibitory Effects of Some Thiazole Derivatives
Çiftçi, Gülsen Akalın; Altıntop, Mehlika Dilek; Temel, Halide Edip; Özdemir, Ahmet; Kaplancıklı, Zafer Asım (Bentham Science Publ LTD, 2017)Background: Cancer is one of the leading causes of morbidity and mortality worldwide and extensive efforts have been devoted to the discovery of new anticancer agents. In the last few decades, the clinical efficacy of ... -
Induction of apoptosis in lung adenocarcinoma and glioma cells by some oxadiazole derivatives
Çiftçi, Gülsen Akalın; Yıldırım, Şafak Ulusoylar; Altıntop, Mehlika Dilek; Kaplancıklı, Zafer Asım (Springer Birkhauser, 2014)Oxadiazoles have received much attention due to their wide range of biological activities including antitumor activity. In this study, we aimed to study apoptotic effects of some 1,3,4-oxadiazole derivatives on human lung ... -
Modification of intracellular free calcium in cultured F2408 embryo fibroblasts by 3-sub substituted-2-thiohydantoin derivatives
Seller, Zerrin; Benkli, Kadriye; Akalın, G; Kaplancıklı, Zafer Asım (Wiley, 2004)3-substituted-2-thiohydantoin derivatives were synthesized and their Structures elucidated by IR, H-1-NMR spectroscopy and elemental analysis. The cytotoxicity of the 2-thiohydantoin derivatives to rat embryo fibroblasts ... -
Synthesis and biological evaluation of thiazoline derivatives as new antimicrobial and anticancer agents
Altıntop, Mehlika Dilek; Kaplancıklı, Zafer Asım; Çiftçi, Gülsen Akalın; Demirel, Rasime (Elsevier France-Editions Scientifiques Medicales Elsevier, 2014)N'-(3,4-Diarylthiazol-2(3H)-ylidene)-2-(arylthio)acetohydrazides were synthesized and evaluated for their antimicrobial activity and cytotoxicity against NIH/3T3 cells. Compound 22 bearing 1-phenyl-1H-tetrazole and ...