Yayıncı "Wiley" Makale Koleksiyonu için listeleme
Toplam kayıt 9, listelenen: 1-9
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Antiepileptic drugs: Impacts on human serum paraoxonase-1
(Wiley, 2017)Serum paraoxonase (PON1) is a key enzyme related to high-density lipoprotein (HDL)-cholesterol particle. It can prevent the oxidation of low-density lipoprotein (LDL) and HDL. The present article focuses on the in vitro ... -
Assessment of the inhibitory effects and molecular docking of some sulfonamides on human serum paraoxonase 1
(Wiley, 2017)Paraoxonase-1 (PON1) is an organophosphate hydrolyzer and antiatherogenic enzyme. Due to the PON1's crucial functions, inhibitors and activators of PON1 must be known for pharmacological applications. In this study, we ... -
Discovery of potent carbonic anhydrase, acetylcholinesterase, and butyrylcholinesterase enzymes inhibitors: The new amides and thiazolidine-4-ones synthesized on an acetophenone base
(Wiley, 2017)Compounds containing nitrogen and sulfur atoms can be widely used in various fields, including industry, medicine, biotechnology, and chemical technology. Among them, amides of acids and heterocyclic compounds have an ... -
Evaluation of chalcones as inhibitors of glutathione S-transferase
(Wiley, 2018)Glutathione S-transferases (GSTs) are the superfamily of multifunctional detoxification isoenzymes and play an important role in cellular signaling. In the present study, potential inhibition effects of chalcones were ... -
Inhibition effects of pesticides on glutathione-S-transferase enzyme activity of Van Lake fish liver
(Wiley, 2018)Glutathione-S-transferases (GSTs) have a function in xenobiotic metabolism. They are a significant multifunctional family with a wide variety of catalytic activities. In the current study, we determined in vitro inhibition ... -
Inhibition properties of some flavonoids on carbonic anhydrase I and II isoenzymes purified from human erythrocytes
(Wiley, 2017)Carbonic anhydrases (CAs, E.C.4.2.1.1) play a critical role in many important physiological events and treatment of some diseases. Flavonoids or phenolic compounds have been discovered as novel CAs inhibitors instead of ... -
Mechanism of capsaicin inhibition of aldose reductase activity
(Wiley, 2017)Aldose reductase (AR) inhibitors play a vital importance as a potential therapeutic and preventive medicine when it comes to hyperglycemia associated diabetic complications. Additionally, capsaicin is used as a food additive ... -
Modification of intracellular free calcium in cultured F2408 embryo fibroblasts by 3-sub substituted-2-thiohydantoin derivatives
(Wiley, 2004)3-substituted-2-thiohydantoin derivatives were synthesized and their Structures elucidated by IR, H-1-NMR spectroscopy and elemental analysis. The cytotoxicity of the 2-thiohydantoin derivatives to rat embryo fibroblasts ... -
Phenolic compounds inhibit the aldose reductase enzyme from the sheep kidney
(Wiley, 2017)Aldose reductase (AR) is the key enzyme for the polyol pathway and responsible for sorbitol accumulation during the hyperglycemia. The present article focuses on the role of phenol, pyrogallol, hydroquinone, resorcinol, ...