Başlık için Farmakoloji Anabilim Dalı listeleme
Toplam kayıt 177, listelenen: 131-150
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New antidepressant drug candidate: Hypericum montbretti extract
(Taylor & Francis LTD, 2011)This study was designed to investigate possible antidepressant-like effects of the extract prepared from the flowers of Hypericum montbretti Spach. (Guttiferae, Clusiaceae). Phytochemical constituents of the methanolic ... -
New beta-diketone and 3,5-dimethyl isoxazole derivatives of theophylline as potential bronchodilator agents
(Ecv-Editio Cantor Verlag Medizin Naturwissenschaften, 1998)Ten new compounds having 7-[(2,4-pentanedione-3-yl)alkyl]- and 7-[(3,5-dimethylisoxazole-4-yl)alkyl]-3,7-dihydro-1,3-dimethyl-1H-purine-2,6-dione structures were synthesized and their bronchodilator activities investigated ... -
New piperidine-hydrazone derivatives: Synthesis, biological evaluations and molecular docking studies as AChE and BChE inhibitors
(Elsevier France-Editions Scientifiques Medicales Elsevier, 2016)Hydrazones and the piperidine ring containing compounds were considered as beneficial substrates in drug design. Therefore, this study was aimed at the synthesis of new benzoyl hydrazones derived from ethyl 4-oxopiperidi ... -
New ß-diketone and 3,5-dimethyl isoxazole derivatives of theophylline as potential bronchodilator agents
(1998)Ten new compounds having 7-[(2,4-pentanedione-3-yl)alkyl]- and 7-[(3,5- dimethylisoxazole-4-yl)alkyl]-3,7-dihydro-1,3-dimethyl-1H-purine-2,6-dione structures were synthesized and their bronchodilator activities investigated ... -
A novel approach for skin infections: Controlled release topical mats of poly (lactic acid)/poly(ethylene succinate) blends containing Voriconazole
(Elsevier Science BV, 2018)The oral and injectable formulations of Voriconazole (VRZ), a known antifungal agent with low solubility, seem to cause severe side effects. Consequently, topical application of VRZ could be advantageous for skin fungal ... -
Novel insight into wound healing properties of methanol extract of Capparis ovata Desf. var. palaestina Zohary fruits
(Wiley, 2018)ObjectivesThe objective of this study was to investigate the wound healing activity of Capparis ovata var. palaestina fruit extract in mice. For this aim, wound healing, invitro antimicrobial and antioxidant activities, ... -
On the relaxant actions of some benzimidazole derivatives on the rat duodenum: Approaches to the mechanism
(1986)[No abstract available] -
The Opiodergic, Serotonergic and Noradrenergic Modulation of Ferulic Acid-Induced Central Analgesia
(Oxford University Press, 2016)… -
Opioid system mediated anti-nociceptive effect of agomelatine in mice
(Pergamon-Elsevier Science LTD, 2016)Aims: This study was planned to examine the antinociceptive efficacy of agomelatine against acute mechanical, thermal, and chemical nociceptive stimuli, as well as to determine the opioid receptor subtypes mediating these ... -
The Other Face of Diabetes Mellitus: Psychiatric and Neurodegenerative Complications: Review
(Ortadogu Ad Pres & Publ Co, 2009)Diabetes mellitus (DM) is a metabolic disorder characterized by chronic hyperglycemia, which is caused by failure in insulin secretion and/or action and it triggers various acute and chronic complications in patients. The ... -
The other face of diabetes mellitus: Psychiatric and neurodegenerative complications: Review [Diabetes mellitus'un diger yüzü: Psikiyatrik ve nörodejeneratif komplikasyonlar]
(Turkiye Klinikleri, 2009)Diabetes mellitus (DM) is a metabolic disorder characterized by chronic hyperglycemia, which is caused by failure in insulin secretion and/or action and it triggers various acute and chronic complications in patients. The ... -
Pharmacological and toxicological effects of gas plant (Dictamnus Albus L.)
(2005)Bu çalışmanın amacı Akgiritotu'nun farmakolojik ve toksikolojik etkilerini araştırmaktır. Yaprak ve meyvalarmdan hazırlanan sulu ekstreler kobay derisi üzerinde 2,4-dinitrobenzen ile karşılaştırmalı olarak test edilmiştir. ... -
Pharmacological effects of rutin
(1991)It is well-known that flavonoids including rutin exert a wide range of pharmacological effects. This study was carried out for further characterization of the pharmacological effect of rutin. A significant rise in the serum ... -
Plasminogen Activator Inhibitor Type-1 Gene 4G/5G Polymorphism Is Associated with Hypertensive Patients in the Turkish Population
(Mary Ann Liebert Inc, 2010)This study has been performed on hypertensive patients in the Turkish population to determine the frequency of 4G/5G polymorphism genotypes of plasminogen activator inhibitor type-1 gene and with the aim of examining the ... -
The Possible Action Mechanisms of Central Analgesic Effect of Protocatechuic Acid
(Oxford University Press, 2016)… -
The possible mechanisms of protocatechuic acid-induced central analgesia
(Elsevier Science BV, 2018)It is aimed to investigate the central antinociceptive effect of protocatechuic acid and the involvement of stimulation of opioidergic, serotonin 5-HT2A/2C. alpha 2-adrenergic and muscarinic receptors in protocatechuic ... -
Potassium and TRP Channels Are Involved in Analgesic Effects of NSAIDs in Tail Immersion Test
(Oxford University Press, 2016)…