Başlık için Farmakoloji Anabilim Dalı listeleme
Toplam kayıt 177, listelenen: 74-93
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Effects of long-term agomelatine treatment on the cognitive performance and hippocampal plasticity of adult rats
(Lippincott Williams & Wilkins, 2015)Agomelatine is an antidepressant with a distinct pharmacological mechanism of action as an MT1 and MT2 receptor agonist and as a 5-HT2C receptor antagonist. We evaluated the chronic effects of agomelatine administration ... -
Effects of phenolic acids on gastrointestinal smooth muscle complications in streptozotocine-induced diabetic rats
(Tubitak Scientific & Technical Research Council Turkey, 2012)Aim: To identify the effects of antioxidants on gastrointestinal smooth muscle complications in 6-week streptozotocine (STZ)-induced diabetic rats. Materials and methods: The following steps were carried out: I. Three weeks ... -
Effects of Prunus spinosa L. Fruits on experimental wound healing [Prunus spinosa L. Meyvelerinin deneysel yara iyileşmesi üzerine etkileri]
(Logos Medical Publishing, 2017)We investigated the wound healing efficacy of the methanol extracts of Prunus spinosa L. fruits using an excisional cutaneous wound model in mice. We used 32 C57/Black mice equally divided into four groups. Group 1 Control, ... -
Effects of Some 1,3,5-Trisubstitued-2-pyrazoline Derivatives on Depression and Anxiety Parameters of Mice
(Pharmaceutical Soc Korea, 2009)The aim of the present study was examining the effects of some 1,3,5-trisubstituted-2-pyrazoline derivatives on depression, anxiety and spontaneous locomotor activity parameters of mice. None of the compounds was effective ... -
Effects of streptozotocin-induced diabetes and insulin on calcium responsiveness of the rat vas deferens
(Pergamon-Elsevier Science LTD, 2006)In the present study, effects of streptozotocin-induced diabetes and insulin treatment on the reactivity of rat vas deferens to KCl and calmidazolium, a calmodulin antagonist, were evaluated and calmodulin levels in vas ... -
Effects of treatment with St. John's Wort on blood glucose levels and pain perceptions of streptozotocin-diabetic rats
(Elsevier Science BV, 2011)This present study was undertaken to examine treating effects of St. John's Wort (SJW) extract on nociceptive perception of STZ-diabetic animals based on its potential antidiabetic and antinociceptive activities. One week ... -
Escitalopram oxalate, a selective serotonin reuptake inhibitor, exhibits cytotoxic and apoptotic effects in glioma C6 cells
(Cambridge University Press, 2011)Objective: Various antidepressants, mainly tricyclic antidepressants (TCAs) and selective serotonin reuptake inhibitors (SSRIs), have been reported to exhibit potent anticancer properties in different cancer cells. In this ... -
Essential Oil Composition of Three Centaurea Species from Turkey: Centaurea aggregata Fisch. & Mey. ex. DC.subsp. aggregata, C. balsamita Lam. and C. behen L.
(2017)The essential oils of Centaurea aggregata subsp. aggregata, C. balsamita and C. behen collected in the same habitat from Turkey, have been investigated. A total of 26, 54 and 26 components were identified in C. aggregata ... -
Ethnobotany of Eskisehir and its environs
(2013)Eskişehir is located in the Central Anatolian province of Turkey. It is included in B3 grid square of Davis. There are more than 1000 plant taxa distributed in this State and its environs and nearly 220 are endemics. The ... -
Evaluation of Antiangiogenic and Antimetastatic Effects of Penicillium chrysogenum Secondary Metabolites
(Medknow Publications & Media Pvt LTD, 2017)Development of resistance to standard therapy and toxic side effects are the major challenges encountered in chemotherapy of colorectal cancer. Increasing evidence has shown the ability of natural products to overcome ... -
Evaluation of neuritogenic activity of cultivated, wild and commercial roots of Gentiana lutea L.
(Elsevier Science BV, 2015)Several natural products have been proven to prevent neurodegenerative disorders by potentiating the action of nerve growth factor (NGF). Among them, secoiridoids have recently attracted interest for their potential use ... -
Evaluation of the Antidiabetic Property of Capparis Ovata Desf. Var. Palaestina Zoh. Extracts Using In vivo and In vitro Approaches
(Bentham Science Publ LTD, 2018)Background and Objective: This paper is focused on evaluating the various biological activities of C. ovata var. palaestina extracts which could beneficially influence diabetes and its complications. Methods: Alloxan-induced ... -
Evaluation of the antileukemic effects of neurokinin-1 receptor antagonists, aprepitant, and L-733,060, in chronic and acute myeloid leukemic cells
(Lippincott Williams & Wilkins, 2019)Neurokinin-1 receptor (NK1R) antagonists are known for their anxiolytic, antiemetic, anticancer, and antiinflammatory effects. Aprepitant is used in vomiting and nausea, which are the most common side-effects of patients ... -
Evaluation of the antithrombotic effects of Crataegus monogyna and Crataegus davisii in the carrageenan-induced tail thrombosis model
(Informa Healthcare, 2015)Context: Crataegus species are widely used as herbal medicines for preventing cardiovascular diseases (CVDs). However, there are no studies on the effects of Crataegus monogyna Jacq. (Rosaceae) and C. davisii Browicz on ... -
Evaluation of the Wound Healing Potentials of Two Subspecies of Hypericum perforatum on Cultured NIH3T3 Fibroblasts
(Wiley-Blackwell, 2011)For centuries, Hypericum perforatum has been used in folk medicine to treat wounds. In the present study, the wound healing activities of extracts of H. perforatum ssp. perforatum (HPP) and H. perforatum ssp. veronense ... -
Extract of Hypericum perforatum blocks caffeine-induced locomotor activity in mice: A possible role of nitric oxide
(John Wiley & Sons LTD, 2007)The present study investigated the effects of HPE on caffeine-induced locomotor activity in mice. Caffeine (416 mg/kg) or saline were given to adult male Swiss-Webster mice, and the locomotor activity was immediately ... -
Extract of hypericum perforatum blocks nicotine-induced locomotor activitiy in mice
(2006)Sunulan çalışmada, farelerde nikotin ile indüklenen lokomotor aktivite üzerine Hiperikum perforatum ekstresinin etkileri incelenmiştir. Çalışmada denek olarak erişkin erkek Swiss-Webster türü fareler kullanıldı. Nikotin ... -
Extract of Hypericum perforatum blocks nicotine-induced locomotor activity in mice
(2006)In the present study, the effects of Hypericum perforatum on nicotine-induced locomotor activity have been investigated in mice. Adult male Swiss-Webster mice were subjects. Nicotine (0.5, 1 and 2 mg/kg) and saline were ...