Yazar "Altan, Vecdi Melih" için Farmakoloji Anabilim Dalı listeleme
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Altered responses to calcium and trifluoperazine in K+-depolarized duodenum from alloxan diabetic rats
Contractile responses to calcium were examined in the K+-depolarized duodenum from normal and alloxan-diabetic rats. In addition, verapamil and trifluoperazine which are well-known calcium channel blocker and calmodulin ... -
Basal and histamine-induced gastric acid secretion in alloxan diabetic rats
Özçelikay, A. T.; Altan, Vecdi Melih; Yıldızoğlu-Arı, N.; AltınKurt, Onur; Onur, F.; Öztürk, Yusuf (1993)1. 1. Effects of alloxan-induced diabetes on the rat gastric acid secretion were investigated using a number of biostatistical models described earlier. 2. 2. Histamine-induced gastric acid secretion was found to be decreased ... -
Beneficial effect of insulin on the decreased gastrointestinal ß-adrenergic responses in streptozotocin-diabetic rats: A contributing role of protein biosynthesis
The beneficial effect of insulin on the decreased gastrointestinal ß-adrenergic responses in experimentally diabetic rats has been reported. The effects of streptozotocin-induced diabetes and insulin on the isolated rat ... -
Calmodulin content and in vitro contractility of duodenum from streptozotocin-induced diabetic rats: Effects of insulin therapy and calmodulin antagonism
Öztürk, Yusuf; Aydın, Süleyman; Özçelikay, A. T.; Altan, Vecdi Melih; YıldızoğluArı, N (Elsevier Science BV, 1997)The effects of experimental diabetes and insulin treatment on the decreased reactivity of isolated rat duodenum to KCI and calmidazolium, a specific calmodulin antagonist, were examined. After 8 weeks of streptozotocin ... -
Decreased Beta-Adrenergic Responses of Rat Small-Intestine Due to Non-Insulin-Dependent Diabetes
Öztürk, Yusuf; Yıldızoğulları, N; Özüarı, A; Özçelikay, At; Altan, Vecdi Melih (Elsevier Sci Ireland LTD, 1990)… -
Diabetic complications in experimental models
Öztürk, Yusuf; Altan, Vecdi Melih; Arı, N. (1998)In this review, the aim is to focus on diabetic complications in experimental models of diabetis. For this purpose, complications, chiefly seen in log-term periods in various systems of animals, such as cardio vascular and ... -
Effect of diabetes on histamine-induced gastric acid secretion in the rat
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Effect of lithium on gastro-intestinal complications in alloxan-diabetic rats
1. 1. Decreased ß-adrenergic and serotonergic responses have been reported in gastro-intestinal tract of experimentally diabetic rats. Effects of lithium on the decreased ß-adrenergic and serotonergic responsiveness of the ... -
The effect of vanadyl treatment on vascular responsiveness of streptozotocin-diabetic rats
Özçelikay, A. T.; Pekiner, C.; Arı, N.; Öztürk, Yusuf; ÖzüArı, A.; Altan, Vecdi Melih (Springer-Verlag, 1994)Vanadyl sulphate has been demonstrated to possess insulin-like effects in streptozotocin (STZ) diabetic rats, including the normalization of hyperglycaemia and the prevention of diabetes-induced cardiac dysfunction. However, ... -
Effects of experimental diabetes and insulin on smooth muscle functions
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The Effects of Glyburide and Insulin on the Cardiac-Performance in Rats With Non-Insulin-Dependent Diabetes-Mellitus
Özüarı, A; Öztürk, Yusuf; Yıldızoğulları, N; Özçelikay, At; Altan, Vecdi Melih (Pergamon-Elsevier Science LTD, 1993)1. The effects Of glyburide were studied on the myocardial contractile force and heart rate in the atria isolated from non-diabetic and non-insulin-dependent diabetic rats (diabetic). 2. In order to examine the myocardial ... -
Increased Alpha(1)-Adrenergic Responsiveness of Alloxan-Diabetic Rat Atria - Effects of Insulin Therapy and Thyroidectomy
Lafçıerol, D; Altan, Vecdi Melih; Öztürk, Yusuf (Pergamon-Elsevier Science LTD, 1994)1. Experimental models of diabetes are increasingly used for the investigation of cardiovascular complications as well as other complications due to diabetes mellitus. However, animal models have been used in relatively ... -
Pharmacological effects of rutin
It is well-known that flavonoids including rutin exert a wide range of pharmacological effects. This study was carried out for further characterization of the pharmacological effect of rutin. A significant rise in the serum ... -
ß-Adrenergic Responsiveness of the Gastrointestinal Tract in Diabetic Rats
Abstract: Recently, decreased gastrointestinal ß-adrenergic responses in experimental diabetes have been demonstrated. Gastrointestinal responses to ß-adrenoceptor agonists are impaired in both insulin-dependent and ...