Kurum Yazarı "Arslan, Rana" Farmakoloji Anabilim Dalı İçin Listeleme
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Analgesic and antispasmodic activities of 2-(2-nitro-phenyl)-1 H-benzimidazole 5-carboxylic acid: Evidence for the importance of the 2-(o-substituted phenyl) group
Aydın, Süleyman; Arslan, Rana; Can, Özgür Devrim (2003)Benzimidazole 5-carboxylic acid derivatives were investigated for analgesic activity in this study. Of the benzimidazole compounds tested, 2-(2-nitro-phenyl)-1 H-benzimidazole 5-carboxylic acid showed remarkable naloxone ... -
Analgesic and antispasmodic activities of 2-(2-nitro-phenyl)-1H-benzimidazole 5-carboxylic acid: evidence for the importance of the 2-(o-substituted phenyl) group
Aydın, Süleyman; Arslan, Rana; Can, Özgür Devrim (Govi-Verlag GMBH, 2003)Benzimidazole 5-carboxylic acid derivatives were investigated for analgesic activity in this study. Of the benzimidazole compounds tested, 2-(2-nitro-phenyl)-1 H-benzimidazole 5-carboxylic acid showed remarkable naloxone ... -
Antinociceptive effect of methanol extract of Capparis ovata in mice
Arslan, Rana; Bektaş, Nurcan (Taylor & Francis LTD, 2010)Context: Capparis ovata Desf. (Capparaceae) grows widely in Turkey. Flower buds and fruits of the plant are used in folk medicine for their analgesic, antirheumatismal, and diuretic effects. Objective:This study evaluated ... -
Antinociceptive, antiinflammatory, and antioxidant activities of the ethanol extract of Crataegus orientalis leaves
Bor, Zeynep; Arslan, Rana; Bektaş, Nurcan; Pirildar, Sevda; Dönmez, Ali Aslan (Tubitak Scientific & Technical Research Council Turkey, 2012)Aim: To determine the in vitro antioxidant activity and to investigate the possible antinociceptive and antiinflammatory effects of the ethanol extract of Crataegus orientalis leaves. The medicinal use of extracts prepared ... -
Antithrombotic effects of ethanol extract of Crataegus orientalis in the carrageenan-induced mice tail thrombosis model
Arslan, Rana; Bor, Zeynep; Bektaş, Nurcan; Meriçli, Ali Hikmet; Öztürk, Yusuf (Pergamon-Elsevier Science LTD, 2011)Introduction: Crataegus species (common name is Hawthorn) are medicinal plants, which have flavonoids, triterpene acids, proanthocyanidins, and organic acids as main constituents, used in the treatment of cardiovascular ... -
The Centrally-Mediated Mechanisms of Action of Ferulic Acid-Induced Antinociception
Bektaş, Nurcan; Arslan, Rana (Marmara University, Fac Medicine, 2016)This study aimed to investigate the central antinociceptive effects of ferulic acid, a common phenolic compound found in various medicinal plants used for pain relief, and the contribution of cholinergic, serotonergic, ... -
Dexketoprofen trometamol loaded solid lipid nanoparticles(SLNs): Formulation, in vitroand in vivoevaluation
Anadolu Üniversitesi, Eczacılık Fakültesi; 0000-0001-9596-0538; 0000-0002-7979-0089; 0000-0002-8041-6844; 0000-0001-9747-8307; 0000-0002-7492-1668; Öztürk, A. Alper; Yenilmez, Evrim; Arslan, Rana; Şenel, Behiye; Yazan, Yasemin (2020)Development, in vitroand in vivoevaluation of dexketoprofen trometamol (DT)-loaded nanosizeddrugdelivery system was aimed in this study. DT-loaded solid lipid nanoparticles (SLNs) were prepared using probe ... -
Evaluation of the Antidiabetic Property of Capparis Ovata Desf. Var. Palaestina Zoh. Extracts Using In vivo and In vitro Approaches
Okur, Mehmet Evren; Polat, Derya C.; Özbek, Hanefi; Yılmaz, Sezen; Yoltas, Ayşegül; Arslan, Rana (Bentham Science Publ LTD, 2018)Background and Objective: This paper is focused on evaluating the various biological activities of C. ovata var. palaestina extracts which could beneficially influence diabetes and its complications. Methods: Alloxan-induced ... -
Evaluation of the antithrombotic effects of Crataegus monogyna and Crataegus davisii in the carrageenan-induced tail thrombosis model
Arslan, Rana; Bektaş, Nurcan; Bor, Zeynep; Şener, Erol (Informa Healthcare, 2015)Context: Crataegus species are widely used as herbal medicines for preventing cardiovascular diseases (CVDs). However, there are no studies on the effects of Crataegus monogyna Jacq. (Rosaceae) and C. davisii Browicz on ... -
Hypoglycemic activity of Capparis ovata desf. var. palaestina zoh. methanol extract
Okur, Mehmet Evren; Özbek, Hanefi; Polat, Derya Çiçek; Yılmaz, Sezen; Arslan, Rana (University Sao Paulo, Conjunto Quimicas, 2018)Caper (Capparis ovata Desf. and Capparis spinosa L.) is naturally widespread in Turkey. Traditionally, buds, fruits, seeds and roots of this plant arc used as tonic, diuretic, anti-rheumatic, expectorant, antidiabetic, and ... -
The imidazoline receptors and ligands in pain modulations
Bektaş, Nurcan; Nemutlu, Dilara; Arslan, Rana (Wolters Kluwer Medknow Publications, 2015)Pain is an unpleasant experience and effects daily routine negatively. Although there are various drugs, many of them are not entirely successful in relieving pain, since pain modulation is a complex process involving ... -
Inhibitory actions of Hypericum perforatum L. on rat vas deferens
Aydın, Süleyman; Arslan, Rana; Öztürk, Nilgün (Wiley-Blackwell, 2001)… -
Nepetalactone: A new opioid analgesic from Nepeta caesarea Boiss.
Aydın, Süleyman; Arslan, Rana; Öztürk, Yusuf; Başer, K. Hüsnü Can (Royal Pharmaceutical Soc Great Britain, 1998)The essential oils of Nepeta species including Nepeta phyllochlamys P. H. Davis, N. nuda L. ssp. nude, and N. caesarea Boiss. have been screened by use of the tail-flick and tail immersion (52.5 degrees C) methods. Of the ... -
The Opiodergic, Serotonergic and Noradrenergic Modulation of Ferulic Acid-Induced Central Analgesia
Bektaş, Nurcan; Arslan, Rana (Oxford University Press, 2016)… -
Pharmacological and toxicological effects of gas plant (Dictamnus Albus L.)
Bu çalışmanın amacı Akgiritotu'nun farmakolojik ve toksikolojik etkilerini araştırmaktır. Yaprak ve meyvalarmdan hazırlanan sulu ekstreler kobay derisi üzerinde 2,4-dinitrobenzen ile karşılaştırmalı olarak test edilmiştir. ... -
Pharmacological effects of tastromine
Arslan, Rana; Öztürk, Yusuf; Aydın, Süleyman (Wiley-Blackwell, 2001)… -
The Possible Action Mechanisms of Central Analgesic Effect of Protocatechuic Acid
Türkmen, Nurcan Bektaş; Arslan, Rana; Aydın, Şule (Oxford University Press, 2016)… -
The possible mechanisms of protocatechuic acid-induced central analgesia
Arslan, Rana; Aydın, Şule; Samur, Dilara Nemutlu; Bektaş, Nurcan (Elsevier Science BV, 2018)It is aimed to investigate the central antinociceptive effect of protocatechuic acid and the involvement of stimulation of opioidergic, serotonin 5-HT2A/2C. alpha 2-adrenergic and muscarinic receptors in protocatechuic ... -
Potassium and TRP Channels Are Involved in Analgesic Effects of NSAIDs in Tail Immersion Test
Arslan, Rana; Türkmen, Nurcan Bektaş (Oxford University Press, 2016)… -
Potential Antithrombotic Effect of Crataegus Species
Arslan, Rana; Bektaş, Nurcan (Assoc Pharmaceutical Teachers India, 2018)Hawthorn (Crataegus), a highly important medicinal and aromatic plant, has been used for many years in the treatment of various diseases. In folk medicine, hawthorn has been used to treat asthma, hyperlipidemia, heart ...