Kurum Yazarı "Bektaş, Nurcan" Farmakoloji Anabilim Dalı İçin Listeleme
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Antinociceptive effect of methanol extract of Capparis ovata in mice
Arslan, Rana; Bektaş, Nurcan (Taylor & Francis LTD, 2010)Context: Capparis ovata Desf. (Capparaceae) grows widely in Turkey. Flower buds and fruits of the plant are used in folk medicine for their analgesic, antirheumatismal, and diuretic effects. Objective:This study evaluated ... -
Antinociceptive, antiinflammatory, and antioxidant activities of the ethanol extract of Crataegus orientalis leaves
Bor, Zeynep; Arslan, Rana; Bektaş, Nurcan; Pirildar, Sevda; Dönmez, Ali Aslan (Tubitak Scientific & Technical Research Council Turkey, 2012)Aim: To determine the in vitro antioxidant activity and to investigate the possible antinociceptive and antiinflammatory effects of the ethanol extract of Crataegus orientalis leaves. The medicinal use of extracts prepared ... -
Antioxidant activity of Punica granatum (Pomegranate) flowers
Bektaş, Nurcan; Öztürk, Nilgün (Elsevier Ireland LTD, 2007)… -
Antithrombotic effects of ethanol extract of Crataegus orientalis in the carrageenan-induced mice tail thrombosis model
Arslan, Rana; Bor, Zeynep; Bektaş, Nurcan; Meriçli, Ali Hikmet; Öztürk, Yusuf (Pergamon-Elsevier Science LTD, 2011)Introduction: Crataegus species (common name is Hawthorn) are medicinal plants, which have flavonoids, triterpene acids, proanthocyanidins, and organic acids as main constituents, used in the treatment of cardiovascular ... -
The Centrally-Mediated Mechanisms of Action of Ferulic Acid-Induced Antinociception
Bektaş, Nurcan; Arslan, Rana (Marmara University, Fac Medicine, 2016)This study aimed to investigate the central antinociceptive effects of ferulic acid, a common phenolic compound found in various medicinal plants used for pain relief, and the contribution of cholinergic, serotonergic, ... -
A computer database for the in vivo dosage in experimental animals (ACD-IDEA)
Öztürk, Y.; Güneş, A.; Babanlı, A.; Abdallah, Qasem M.A.; Topbaş-Can, O. D.; Bektaş, N.; Aydın, S.; Öztürk, Yusuf; Güneş, Ali; Babanlı, Ahmad; Abdallah, Qasem M.A.; Topbaş-Can, O. D.; Bektaş, Nurcan; Aydın, Süleyman (Wiley-Blackwell, 2004)… -
Effect of phenolic acids on functions of rat aorta, vas deferens and on metabolic changes in streptozotocin-induced diabetes
Bektaş, Nurcan; Öztürk, Yusuf (Medknow Publications & Media Pvt LTD, 2012)Objectives: This study aimed to investigate the effects of antioxidant treatment on streptozotocin (STZ)-induced diabetic metabolic and smooth muscle (SM) complications in rats. Materials and Methods: Threeweeks after STZ ... -
Effects of phenolic acids on gastrointestinal smooth muscle complications in streptozotocine-induced diabetic rats
Bektaş, Nurcan; Öztürk, Yusuf (Tubitak Scientific & Technical Research Council Turkey, 2012)Aim: To identify the effects of antioxidants on gastrointestinal smooth muscle complications in 6-week streptozotocine (STZ)-induced diabetic rats. Materials and methods: The following steps were carried out: I. Three weeks ... -
Evaluation of the antithrombotic effects of Crataegus monogyna and Crataegus davisii in the carrageenan-induced tail thrombosis model
Arslan, Rana; Bektaş, Nurcan; Bor, Zeynep; Şener, Erol (Informa Healthcare, 2015)Context: Crataegus species are widely used as herbal medicines for preventing cardiovascular diseases (CVDs). However, there are no studies on the effects of Crataegus monogyna Jacq. (Rosaceae) and C. davisii Browicz on ... -
The imidazoline receptors and ligands in pain modulations
Bektaş, Nurcan; Nemutlu, Dilara; Arslan, Rana (Wolters Kluwer Medknow Publications, 2015)Pain is an unpleasant experience and effects daily routine negatively. Although there are various drugs, many of them are not entirely successful in relieving pain, since pain modulation is a complex process involving ... -
The Opiodergic, Serotonergic and Noradrenergic Modulation of Ferulic Acid-Induced Central Analgesia
Bektaş, Nurcan; Arslan, Rana (Oxford University Press, 2016)… -
The possible mechanisms of protocatechuic acid-induced central analgesia
Arslan, Rana; Aydın, Şule; Samur, Dilara Nemutlu; Bektaş, Nurcan (Elsevier Science BV, 2018)It is aimed to investigate the central antinociceptive effect of protocatechuic acid and the involvement of stimulation of opioidergic, serotonin 5-HT2A/2C. alpha 2-adrenergic and muscarinic receptors in protocatechuic ... -
Potential Antithrombotic Effect of Crataegus Species
Arslan, Rana; Bektaş, Nurcan (Assoc Pharmaceutical Teachers India, 2018)Hawthorn (Crataegus), a highly important medicinal and aromatic plant, has been used for many years in the treatment of various diseases. In folk medicine, hawthorn has been used to treat asthma, hyperlipidemia, heart ... -
The Role of TRP and K+ Ion Channels in Analgesic Effect of NSAIDs
Arslan, Rana; Bektaş, Nurcan (Marmara University, Inst Health Sciences, 2018)Objective: We aimed to clarify the possible contributions of TRP and voltage-dependent K+ channels to the analgesic effects of diclofenac, ketoprofen, etodolac, and dipyrone using the nonselective TRP channel blocker ... -
Valnoctamide: The effect on relieving of neuropathic pain and possible mechanisms
Samur, Dilara Nemutlu; Arslan, Rana; Aydın, Şule; Bektaş, Nurcan (Elsevier Science BV, 2018)The purpose of this study is to assess the possible anti-allodynic and antihyperalgesic effect of valnoctamide, an amide derivative of valproic acid, at the doses of 40, 70 and 100 mg/kg (i.p.) in neuropathic pain model ... -
Zonisamide: Antihyperalgesic efficacy, the role of serotonergic receptors on efficacy in a rat model for painful diabetic neuropathy
Bektaş, Nurcan; Arslan, Rana; Öztürk, Yusuf (Pergamon-Elsevier Science LTD, 2014)Aims: The purpose of this study was to compare the changes of antihyperalgesic effectiveness of zonisamide (25 and 50 mg/kg), an antiepileptic drug, on the early and late phases of neuropathy and to investigate the role ...