New alkaloids from Bongardia chrysogonum

Abstract

Two new alkaloids, 17-desoxy-cis-lamprolobine (1) and bonzakaline (2), along with the known alkaloids lupanine (3) and palmatrubine (4), have been isolated from the ethanolic extracts of Bongardia chrysogonum. Compounds 1 and 2 have shown antibacterial activity against Proteus mirabilis, Proteus vulgaris, Klebsiella pneumoniae, Escherichia coli and Shigella dysenteriae. The structure elucidation was performed by using various spectroscopic methods including 2D NMR techniques(1,2).