Kurum Yazarı "Şenel, Behiye" Makale Koleksiyonu İçin Listeleme
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Development of paclitaxel-loaded liposomal systems with anti-her2 antibody for targeted therapy
Büyükköroğlu, Gülay; Şenel, Behiye; Başaran, Ebru; Gezgin, Seval (Pharmacotherapy Group, 2016)Purpose: To develop liposome formulations containing monoclonal antibody anti-HER2 (MabHer2), and Paclitaxel (PTX). Methods: Seven different liposomal systems containing PTX, or MabHer2 or a combination of PTX and MabHer2 ... -
Dexketoprofen trometamol loaded solid lipid nanoparticles(SLNs): Formulation, in vitroand in vivoevaluation
Anadolu Üniversitesi, Eczacılık Fakültesi; 0000-0001-9596-0538; 0000-0002-7979-0089; 0000-0002-8041-6844; 0000-0001-9747-8307; 0000-0002-7492-1668; Öztürk, A. Alper; Yenilmez, Evrim; Arslan, Rana; Şenel, Behiye; Yazan, Yasemin (2020)Development, in vitroand in vivoevaluation of dexketoprofen trometamol (DT)-loaded nanosizeddrugdelivery system was aimed in this study. DT-loaded solid lipid nanoparticles (SLNs) were prepared using probe ... -
Graphene quantum dots: Synthesis, characterization, cell viability, genotoxicity for biomedical applications
Şenel, Behiye; Demir, Neslihan; Büyükköroğlu, Gülay; Yıldız, Mustafa (Elsevier, 2019)We report the synthesis and applications of a novel N-doped graphene quantum dots (GQDs) using hydrothermal reaction between citric acid and p-aminophenol. The synthesized N-doped GQDs have been characterized physico-chemically ... -
In vitro preliminary studies of chitooligosaccharide coated nanostructured lipidic nanoparticles for efficient gene delivery
Şenel, Behiye (Marmara University, 2019)Gene therapy is generally defined as the transfer of genetic material to cells to treat a disease or at least improve the clinical condition of a patient. The most commonly used vectors in gene therapy are viral and non-viral ... -
Preparation and In Vitro Evaluation of DNA-Bonded Polymeric Nanoparticles as New Approach for Transcutaneous Vaccination
Büyükköroğlu, Gülay; Şenel, Behiye; Karabacak, Rukiye B. (Colegio Farmaceuticos Provincia De Buenos Aires, 2017)The objective of this study was to develop a DNA vaccine, which can be applied topically as a cream containing plasmid DNA (pDNA)/cationic polymeric nanoparticle (PP) complex. The selected pDNA was pCMV-S encoding hepatitis ... -
Preparation and in vitro evaluation of DNA-bonded polymeric nanoparticles as new approach for transcutaneous vaccination
Büyükköroğlu, Gülay; Şenel, Behiye; Karabacak, Rukiye B. (Colegio de Farmaceuticos de la Provincia de Buenos Aires, 2017)The objective of this study was to develop a DNA vaccine, which can be applied topically as a cream containing plasmid DNA (pDNA)/cationic polymeric nanoparticle (PP) complex. The selected pDNA was pCMV-S encoding hepatitis ... -
Preparation and in vitro evaluation of vaginal formulations including siRNA and paclitaxel-loaded SLNs for cervical cancer
Büyükköroğlu, Gülay; Şenel, Behiye; Başaran, Ebru; Yenilmez, Evrim; Yazan, Yasemin (Elsevier Science BV, 2016)Cervical cancer is one of the most life threatening types of cancer among women and is generally resistant to chemotherapy. The objective of this study was to prepare a vaginal suppository containing a chemotherapeutic ... -
The simultaneous delivery of paclitaxel and Herceptin (R) using solid lipid nanoparticles: In vitro evaluation
Büyükköroğlu, Gülay; Şenel, Behiye; Gezgin, Seval; Tan Dinh (Elsevier Science BV, 2016)This study was aimed at formulating Paclitaxel (R)-loaded solid lipid nanoparticles (SLN) complexed with Herceptin (R). The physicochemical characterizations of the SLNs/Herceptin (R) complexes such as particle size and ...