Yazar "Can, Özgür Devrim" için Makale Koleksiyonu listeleme
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Anticholinesterase activity screening of some novel dithiocarbamate derivatives including piperidine and piperazine moieties
Levent, Serkan; Çevik, Ulviye Acar; Sağlık, Begüm Nurpelin; Özkay, Yusuf; Can, Özgür Devrim; Özkay, Ümide Demir; Uçucu, Ümit (Taylor & Francis LTD, 2017)The present study was undertaken to synthesize some novel lipophilic piperazine and piperidinedithiocarbamates and investigate their inhibitory potencies against cholinesterase enzymes. In the synthetic studies, 44 new ... -
New pyrazoline derivatives and their antidepressant activity
Kaplancıklı, Zafer Asım; Özdemir, Ahmet; Turan, Gülhan; Altıntop, Mehlika Dilek; Can, Özgür Devrim (Elsevier France-Editions Scientifiques Medicales Elsevier, 2010)Some triazolo-pyrazoline derivatives were synthesized to investigate their potential antidepressant activities. The chemical structures of the compounds were elucidated by IR, NMR and FAB(+)-MS spectral data and elemental ... -
Synthesis and analgesic activity of some acetamide derivatives
Kaplancıklı, Zafer Asım; Altıntop, Mehlika Dilek; Turan, Gülhan; Özdemir, Ahmet; Can, Özgür Devrim (Informa Healthcare, 2012)In the present study, some acetamide derivatives were synthesized and their potential analgesic activities were investigated. N-(benzothiazol-2-yl)-2-[(1-substituted-1H-tetrazol-5-yl) thio] acetamide derivatives were ... -
Synthesis and anti-nociceptive, anti-inflammatory activities of new aroyl propionic acid derivatives including N-acylhydrazone motif
Turan, Gülhan; Yurttaş, Leyla; Kaplancıklı, Zafer Asım; Can, Özgür Devrim; Özkay, Ümide Demir (Springer Birkhauser, 2015)In the present study, new 4-[4-[2-(2-(4-substituted benzylidene)hydrazinyl)-2-oxoethoxy]phenyl]-4-oxobutanoic acid derivatives were synthesized, and their anti-nociceptive and anti-inflammatory activities were investigated. ... -
Synthesis and antinociceptive activities of some pyrazoline derivatives
Kaplancıklı, Zafer Asım; Turan, Gülhan; Özdemir, Ahmet; Can, Özgür Devrim; Chevallet, Pierre (Elsevier France-Editions Scientifiques Medicales Elsevier, 2009)In the present study, some pyrazoline derivatives were synthesized to investigate their potential antinociceptive activities. 1-[(Benzoxazole/benzimidazole-2-yl)thioacetyl]pyrazoline derivatives were obtained by reacting ... -
Synthesis and Evaluation of New 1,3,4-Thiadiazole Derivatives as Antinociceptive Agents
Altıntop, Mehlika Dilek; Can, Özgür Devrim; Özkay, Ümide Demir; Kaplancıklı, Zafer Asım (MDPI AG, 2016)In the current work, new 1,3,4-thiadiazole derivatives were synthesized and investigated for their antinociceptive effects on nociceptive pathways of nervous system. The effects of these compounds against mechanical, thermal ... -
Synthesis and Evaluation of New 1,5-Diaryl-3-[4-(methyl-sulfonyl)phenyl]-4,5-dihydro-1H-pyrazole Derivatives as Potential Antidepressant Agents
Özdemir, Ahmet; Altıntop, Mehlika Dilek; Kaplancıklı, Zafer Asım; Can, Özgür Devrim; Özkay, Ümide Demir; Turan, Gülhan (MDPI, 2015)In an effort to develop potent antidepressant agents, new pyrazoline derivatives 2a-s were synthesized and evaluated for their antidepressant-like activity by tail suspension test (TST) and modified forced swimming test ... -
Synthesis of Some Novel Thiadiazole Derivative Compounds and Screening Their Antidepressant-Like Activities
Can, Nafiz Öncü; Can, Özgür Devrim; Osmaniye, Derya; Özkay, Ümide Demir (MDPI, 2018)Novel thiadiazole derivatives were synthesized through the reaction of acetylated 2-aminothiadiazole and piperazine derivatives. The chemical structures of the compounds were clarified by Infrared Spectroscopy (IR), H-1 ...