Konu "Dithiocarbamate" için Makale Koleksiyonu listeleme
Toplam kayıt 13, listelenen: 1-13
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Anticholinesterase activity screening of some novel dithiocarbamate derivatives including piperidine and piperazine moieties
(Taylor & Francis LTD, 2017)The present study was undertaken to synthesize some novel lipophilic piperazine and piperidinedithiocarbamates and investigate their inhibitory potencies against cholinesterase enzymes. In the synthetic studies, 44 new ... -
New Cyclohexylamine-dithiocarbamate Derivatives as Potential Anti-microbial Agents
(Bentham Science Publ LTD, 2017)Background: In this study, 2-(substituted-sulfanyl)-N, N-dicyclohexylacetamide derivatives (2a-2g) and 2-(dicyclohexylamino)-2-oxoethyl-1-substituted carbodithioate derivatives (2h-2m) were synthesized and screened for ... -
Novel imidazole derivatives as antifungal agents: Synthesis, biological evaluation, ADME prediction and molecular docking studies
(Taylor & Francis LTD, 2019)A series of 2-(substituteddithiocarbamoyl)-N-[4-((1H-imidazol-1-yl)methyl)phenyl]acetamide derivatives was designed and synthesized to combat the increasing incidence of drug-resistant fungal infections. All synthesized ... -
Synthesis and antimicrobial activity evaluation of new dithiocarbamate derivatives bearing thiazole/benzothiazole rings
(Taylor & Francis LTD, 2016)The synthesis of 2-(substituted phenyl)-2-oxoethyl 4-(pyrimidin-2-yl)piperazin-1-carbodithiodate (A1-A24) derivatives and 2-(4-substituted thiazol-2-ylamino)-2-oxoethyl 4-(pyrimidin-2-yl)piperazin-1-carbodithiodate (B1-B14) ... -
Synthesis and Biological Activity of Thiazole Dithiocarbamate Derivatives
(Bentham Science Publ LTD, 2014)In this study, we aimed at the synthesis of new 2-((5-substituted-4-methylthiazol-2-yl) amino)-2-oxoethyl 4-substitutedpiperazine- 1-carbodithioate derivatives and their antibacterial, antifungal, antioxidant and AChE ... -
Synthesis and Biological Evaluation of a Series of Dithiocarbamates as New Cholinesterase Inhibitors
(Wiley-V C H Verlag GMBH, 2013)In the present paper, a novel series of dithiocarbamates was synthesized via the treatment of 4-(trifluoromethyl)benzyl chloride with appropriate sodium salts of N,N-disubstituted dithiocarbamic acids. H-1 NMR, mass spectral ... -
Synthesis and Biological Evaluation of Some Pyrazoline Derivatives Bearing a Dithiocarbamate Moiety as New Cholinesterase Inhibitors
(Wiley-V C H Verlag GMBH, 2013)In the present study, new pyrazoline derivatives were synthesized via the reaction of 1-(chloroacetyl)-3-(2-furyl)-5-aryl-2-pyrazolines with sodium salts of N,N-disubstituted dithiocarbamic acids. Each derivative was ... -
Synthesis and Evaluation of Anti-acetylcholinesterase Activity of Some Benzothiazole Based New Piperazine-dithiocarbamate Derivatives
(Georg Thieme Verlag Kg, 2015)In this present study some benzothiazole derivatives bearing piperazine and thiocarbamate moieties were synthesized and their potential anticholinesterase properties were investigated. A set of 30 new compounds of ... -
Synthesis and evaluation of new benzodioxole-based dithiocarbamate derivatives as potential anticancer agents and hCA-I and hCA-II inhibitors
(Elsevier France-Editions Scientifiques Medicales Elsevier, 2017)In the current work, new benzodioxole-based dithiocarbamate derivatives were synthesized via the reaction of N-(1,3-benzodioxol-5-ylmethyl)-2-chloroacetamide with appropriate sodium salts of N,N-disubstituted dithiocarbamic ... -
Synthesis of Novel 4-(Dimethylaminoalkyl) piperazine-1-carbodithioate Derivatives as Cholinesterase Inhibitors
(Bentham Science Publ LTD, 2017)Background: Carbamate compounds have attracted a great deal of interest in medicinal chemistry due to their inhibition potential against cholinesterase enzymes. Method: Hence, this study was undertaken to synthesize new ... -
Synthesis of Some Benzothiazole Based Piperazine-Dithiocarbamate Derivatives and Evaluation of Their Anticancer Activities
(Bentham Science Publ LTD, 2011)Some benzothiazole derivatives bearing piperazine and dithiocarbamate moieties were synthesized in order to investigate their anticancer activity. The structures of the obtained compounds were confirmed by spectral data ... -
Synthesis, Antibacterial and Antifungal Activities of Some Carbazole Dithiocarbamate Derivatives
(Bentham Science Publ LTD, 2011)In this study, we aimed at the synthesis of new N, N-disubstituted dithiocarbamoic acid, 2-[(9-ethyl-9H-carbazol-3-yl) amino]-2-oxoethyl esters and their antimicrobial evaluations. The chemical structures of the compounds ... -
Synthesis, anticandidal activity, and cytotoxicity of some thiazole derivatives with dithiocarbamate side chains
(Scientific Technical Research Council Turkey-Tubitak, 2014)Some thiazole derivatives bearing dithiocarbamic acid esters were synthesized in order to investigate their anticandidal activity and cytotoxicity. The structures of the obtained final compounds (6a-j) were confirmed by ...