Synthesis and Antiviral Activity of Some (3,4-Diaryl-3H-Thiazol-2-Ylidene)Pyrimidin-2-Yl Amine Derivatives

Abstract

Thirteen new (3,4-diaryl-3H-thiazol-2-ylidene) pyrimidin-2-yl amine derivatives were synthesized by reacting 1-aryl-3-pyrimidin-2-yl-thiourea derivatives and phenacyl bromides in absolute ethanol. The solid that separated was filtered and recrystallized from ethanol. The structures of the synthesized compounds were confirmed by elemental analyses and (1)H NMR, (13)C NMR, and EI-MS spectral data.