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Toplam kayıt 61, listelenen: 41-50
Formulation and in vitro-in vivo evaluation of piribedil solid lipid micro- and nanoparticles
(Taylor & Francis LTD, 2001)
Modification of the dissolution rate and, thus, the enhancement of the bioavailability of a dopaminergic drug, piribedil, which has a low aqueous solubility and short elimination half-life have been the aim in this study. ...
Preparation of prolonged release clarithromycin microparticles for oral use and their in vitro evaluation
(Pharmaceutical Soc Korea, 2006)
Prolonged release microparticles of clarithromycin (CL) were prepared using Eudragit RL 100 and RS 100 by spray-drying and casting-drying techniques. For the characterization of those microparticles, preparation yield, ...
Microencapsulation of ketorolac tromethamine by means of a coacervation phase separation technique induced by the addition of non-solvent
(Taylor & Francis LTD, 1998)
Ketorolac tromethamine (KT) is a non-steroidal drug with potent analgesic and anti-inflammatory activity and is absorbed rapidly (T-max (1.0h) with an efficiency >87% following oral and intramuscular administration. The ...
A Polarographic Study on Dipyridamole and Its Determination in Commercial Tablets
(Marcel Dekker Inc, 1991)
The direct current polarographic behaviour of dipyridamole, a coronary vasodilator, in the supporting electrolyte consisting of 0.2 M KCl, 20% (v/v) ethanol and buffer solutions is described in this study. Morphologically ...
Enhancement in dissolution pattern of piribedil by molecular encapsulation with beta-cyclodextrin
(Prous Science, Sa, 2006)
The aim of this was to improve the dissolution behavior of piribedil by molecular encapsulation with beta-cyclodextrin (beta-CD). Toward this aim, physical mixing, co-grinding, and spray-drying methods were used to prepare ...
Studies on vaginal bioadhesive tablets of acyclovir
(Govi-Verlag GMBH, 2000)
Bioadhesive vaginal tablets were prepared using poly(acrylic acid) (PAA); Methylcellulose (MC), carboxymethyl cellulose (CMC), hydroxypropyl cellulose (HPC) and hydroxypropylmethyl cellulose (HPMC) as bioadhesive polymers ...
Gamma-aminobutyric acid loaded halloysite nanotubes and in vitro-in vivo evaluation for brain delivery
(Elsevier Science BV, 2015)
Gamma-aminobutyric acid (GABA) is a key neurotransmitter where it usually inhibits impulse transmission. GABA release blockage or postsynaptic reaction were determined to provoke epileptic convulsions. The aim of the present ...
Effects of Different Derivatives of Eudragit Polymer on Entrapment Efficiency, In Vitro Dissolution, Release Kinetics and Cell Viability Results on Extended Release Flurbiprofen Loaded Nanomedicines
(Colegio Farmaceuticos Provincia De Buenos Aires, 2018)
The purpose of the present investigation was to design and compare the release characteristics of sustained-release formulations of Flurbiprofen (FLB) loaded nanoparticles (NPs) by using spray-dryer technique using Eudragit ...
Olopatadine hydrochloride loaded Kollidon (R) SR nanoparticles for ocular delivery: Nanosuspension formulation and in vitro-in vivo evaluation
(Elsevier Science BV, 2019)
Introduction: Allergic eye diseases includes a spectrum of diseases, with each state being characterized by a complicated immunopathology. In the present study, polymeric Kollidon (R) SR nanoparticles loaded with olopatadine ...
Chitosan gel formulations containing egg yolk oil and epidermal growth factor for dermal burn treatment
(Govi-Verlag Pharmazeutischer Verlag GMBH, 2015)
In the present study chitosan based gel formulations containing Egg Yolk Oil (EYO) and Epidermal Growth Factor (EGF) were formulated successfully aiming at enhanced topical treatment of dermal burns the combination of ...