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Toplam kayıt 20, listelenen: 1-10
Acute drug poisonings in Eskisehir, Turkey: A retrospective study [Eskişehirde akut i·laç zehirlenmeleri: Retrospektif bir çahşma]
(2013)
The aim of this study was to characterize acute drug-poisoning cases admitted to the Adult Emergency Service of ESOGU Medicine Faculty Hospital, Turkey. All acute drug-poisoning cases admitted to the emergency service from ...
Effects of Everolimus in Combination with Sildenafil in Monocrotaline-induced Pulmonary Hypertension in Rats
(Humana Press Inc, 2012)
In our study, we investigated the efficacy of everolimus in combination with sildenafil on hemodynamic and morphological parameters in rats with monocrotaline-induced pulmonary hypertension (PH). Right ventricular pressure ...
Acute and Subchronic Toxic Effects of the Fruits of Physalis peruviana L.
(Hindawi Publishing Corporation, 2013)
The fruit of Physalis peruviana L. (PPL) has been traditionally used as antispasmodic, diuretic, antiseptic, sedative, and analgesic all over the world. We aimed to perform qualitative content analysis of the fruits of PPL ...
The effects of gender difference on monocrotaline-induced pulmonary hypertension in rats
(SAGE Publications LTD, 2013)
The present study aimed to compare the effect of gender difference on hemodynamic consequences in the development of monocrotaline (MCT)-induced pulmonary hypertension in rat. The effect of antioxidant enzyme systems on ...
Reproductive toxicity after levetiracetam administration in male rats: Evidence for role of hormonal status and oxidative stress
(Public Library Science, 2017)
Levetiracetam (LEV) is an antiepileptic drug commonly used in the treatment of epilepsy because of its excellent safety profile in all age groups. It is remarkable that there are no studies evaluating the toxic effects of ...
Sertraline-induced reproductive toxicity in male rats: evaluation of possible underlying mechanisms
(Wolters Kluwer Medknow Publications, 2017)
This study was conducted to clarify the toxic effects of sertraline (SRT) on the reproductive system of male rats and to elucidate the underlying mechanisms. Rats were treated orally with SRT at doses of 5, 10, and 20 mg ...
Biotransformation of abietic acid by fungi and biological evaluation of its metabolites
(Elsevier Sci LTD, 2017)
Biotransformation of abietic acid was carried out initially using 28 different microbial strains. Among the evaluated, Mucor ramannianus produced a known metabolite namely 2 alpha-hydroxy-dehydroabietic acid whereas ...
Evaluation of the reproductive toxicity of naproxen sodium and meloxicam in male rats
(SAGE Publications LTD, 2015)
Nonsteroidal anti-inflammatory drugs that are cyclooxygenase (COX) enzyme inhibitors have generally been used in short-term pain management and also to treat inflammation chronically. It is known that COX enzyme and ...
Evidence for cardiotoxicity associated with sertraline in rats
(Royal Soc Chemistry, 2018)
Sertraline is an antidepressant that is frequently prescribed to treat depression, obsessive-compulsive disorder, panic disorder, and anxiety. This drug had a safe cardiotoxicity profile, until the reporting of cases of ...
Toxic Effects of Trazodone on Male Reproductive System via Disrupting Hypothalamic-Pituitary-Testicular Axis and Inducing Testicular Oxidative Stress
(Hindawi LTD, 2018)
Depression and anxiety are recognized as public health problems. Epidemiological studies have shown that depression and anxiety often occur during reproductive ages between 20 and 60 years of age in males. Trazodone is one ...