Yazar "Karaca Gencer, Hülya" için Makale Koleksiyonu listeleme
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Design, synthesis, and evaluation of novel 2-phenylpropionic acid derivatives as dual COX inhibitory-antibacterial agents
Karaca Gencer, Hülya; Çevik, Ulviye Acar; Kaya Çavuşoğlu, Betül; Sağlık, Begüm Nurpelin; Levent, Serkan; Atlı Eklioğlu, Özlem; Kaplancıklı, Zafer Asım (Taylor & Francis LTD, 2017)A series of 2-(4-substitutedmethylphenyl) propionic acid derivatives (6a-6m) were synthesized, characterized and evaluated for cyclooxygenase (COX) enzyme inhibitory and antimicrobial activity. Test compounds that exhibited ... -
New 1,4-dihydro[1,8]naphthyridine derivatives as DNA gyrase inhibitors
Karaca Gencer, Hülya; Levent, Serkan; Çevik, Ulviye Acar; Özkay, Yusuf; Ilgın, Sinem (Pergamon-Elsevier Science LTD, 2017)Owing to the growing need for novel antibacterial agents, we synthesized a novel series of fluoroquinolones including 7-substituted-1-(2,4-difluoropheny1)-6-fluoro-4-oxo-1,4-dihydro[1,8]naphthyridine-3-carboxylic acid ... -
New Benzimidazole-1,2,4-Triazole Hybrid Compounds: Synthesis, Anticandidal Activity and Cytotoxicity Evaluation
Karaca Gencer, Hülya; Çevik, Ulviye Acar; Levent, Serkan; Sağlık, Begüm Nurpelin; Korkut, Büşra; Özkay, Yusuf; Öztürk, Yusuf (MDPI AG, 2017)Owing to the growing need for antifungal agents, we synthesized a new series 2-((5-(4-(5-substituted-1H-benzimidazol-2-yl)phenyl)-4-substituted-4H-1,2,4-triazol-3-yl)thio)-1-(substituted phenyl)ethan-1-one derivatives, ... -
Synthesis of thiazole-phenylacetic acid compounds as dual antibacterial-COX enzymes inhibitors
Karaca Gencer, Hülya (Çukurova University, Fac Medicine, 2017)Purpose: Present a new potential dual drug for patient suffering both inflammation and infection was aim of this study therefore investigation of anti-inflammatory and antimicrobial activity of new thiazole-phenylacetic ...