Synthesis of some 4-pyrrolylphenylthiazole derivatives and investigation of their antimicrobial activities

Abstract

In this study, some 2-substituted 4-[4-(pyrrol-1-yl)phenyl] thiazole derivatives were obtained reacting some 1,4-dicarbonyl compounds and 2-substituted 4-(4-aminophenyl) thiazoles. The latters were prepared by hydrolyzing of 2-substituted 4-(4-acetylaminophenyl)thiazoles. The antibacterial and antifungal activities of the pyrrole compounds were investigated and no considerable activity was obtained.