| dc.contributor.author | Yazan, Yasemin | |
| dc.contributor.author | Bozan, Berrin | |
| dc.date.accessioned | 2019-10-19T16:02:42Z | |
| dc.date.available | 2019-10-19T16:02:42Z | |
| dc.date.issued | 1995 | |
| dc.identifier.issn | 0031-7144 | |
| dc.identifier.uri | https://hdl.handle.net/11421/13882 | |
| dc.description | PubMed: 7700964 | en_US |
| dc.description.abstract | A modified and simple HPLC procedure has been developed for verapamil in plasma. Plasma samples have been vortex-mixed and centrifuged without any need of extraction. The analysis has been performed on a C20 reversed-phase column with fluorometric detection using 5,6-benzoquinoline as an internal standard. Standard curve has been found to be linear for concentrations from 30 to 1000 ng/ml (plasma) for verapamil and no potential source of interference was present. The method has the advantages of speed, small sample requirement and reproducibility. Applicability of the method has been demonstrated by a pharmacokinetic study in 7 rabbits which received a single dose of 0.25 mg verapamil hydrochloride by intravenous administration. | en_US |
| dc.language.iso | eng | en_US |
| dc.rights | info:eu-repo/semantics/closedAccess | en_US |
| dc.title | Rapid analysis of verapamil in plasma by reversed phase HPLC | en_US |
| dc.type | article | en_US |
| dc.relation.journal | Pharmazie | en_US |
| dc.contributor.department | Anadolu Üniversitesi, Eczacılık Fakültesi, Farmasötik Teknoloji Anabilim Dalı | en_US |
| dc.identifier.volume | 50 | en_US |
| dc.identifier.issue | 2 | en_US |
| dc.identifier.startpage | 117 | en_US |
| dc.identifier.endpage | 119 | en_US |
| dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US] |
| dc.contributor.institutionauthor | Yazan, Yasemin | |
| dc.contributor.institutionauthor | Bozan, Berrin | |
