Ara
Toplam kayıt 14, listelenen: 1-10
Lead toxicity and biochemical characterization of $delta$ - ALAD on endemic prawn, Palaemonetes turcorum
(2010)
Bu çalışmada kurşunun yurdumuz için endemik olan Palaemonetes turcorum'a toksik etkisi, bu türe ait $delta$ - Amino Levulinik Asit Dehidrataz (ALAD; Porfobilinojen sentaz; E.C.4.2.1.24) enzimi ile etkileşimi ve enzimin ...
Examining impacts of ceranib-2 on the proliferation, morphology and ultrastructure of human breast cancer cells
(Springer, 2016)
Acid ceramidases are enzymes with a vital role in metabolizing ceramide to sphingosine-1-phosphate that is an antiproliferative metabolite in the ceramide pathway. Inhibition of exogenous ceramides with ceramidase inhibitors ...
The efects of thallium acatate on hepatopancreatic cells of Gammarus pulex (Crustacea: Amphipoda)
(2011)
Çalışmamızda, talyumun toksik etkisinin, çevre kirliliği için hassas bir indikator canlı olan Gammarus pulex'de meydana getirmiş olduğu sitolojik değişiklikler çalışılmıştır. Talyum asetat ile yapılan çalışmalarda bu ...
Titanyum Dioksitin A549 Hücreleri Üzerindeki Apoptotik Etkileri
(2017)
Metal temelli bileşikler potansiyel etkilerinden ve az toksisiteye neden olduklarından dolayı uzun zamandır kullanılmaktadır. Metal bileşik sisplatin çeşitli kanser türlerine karşı tıbbi olarak kullanılmış ve yan etkiler ...
Mutagenic activities of ten imidazole derivatives in Salmonella typhimurium
(Springer, 2007)
Ten imidazole derivatives were tested for mutagenicity in Salmonella typhimurium strains TA98 and TA100 both in the absence and presence of metabolic activation by the microsomal fraction S9 mix. In a general manner, ...
Cytotoxic, anti-proliferative and apoptotic effects of silver nitrate against H-ras transformed 5RP7
(Springer, 2016)
Metal based drugs have successfully been used in both the detection and treatment of different disease states. The antibacterial features of metal ion silver are well documented. Most recently, metal ion silver has been ...
Melatonin induces antiproliferative activity through modulation of apoptotic pathway in H-ras oncogene transformed 5RP7 cells
(Tubitak Scientific & Technical Research Council Turkey, 2015)
In the present study, cytotoxic and apoptotic effects of melatonin were investigated on H-ras oncogene transformed rat embryo fibroblast 5RP7 cells. Melatonin inhibited cell growth and induced apoptosis in 5RP7 cells. We ...
The apoptotic and genomic studies on A549 cell line induced by silver nitrate
(SAGE Publications LTD, 2017)
Lung cancer is the leading cause of male cancer deaths worldwide. Metal-based anticancer drugs have evolved significantly during the past decades. Recently, silver ions have been investigated for their anticancer effects. ...
Potential Recruiting and Hepatoprotective Effects of Ellagic Acid in D-Galactosamine-Induced Liver Damage in Rats
(Zoological Soc Pakistan, 2017)
The present study aims to investigate the therapeutic and protective effects of ellagic acid (EA) on the toxicity of the liver induced by D-Galactosamine (D-GaIN) in rats. With this in mind, the rats were categorized into ...
The Potential Protective Effects of 2-aminoethyl Diphenylborinate against Inner Ear Acoustic Trauma: Experimental Study Using Transmission and Scanning Electron Microscopy
(Aves, 2015)
OBJECTIVE: In this prospective experimental study, we investigated the preventive effects of 2-aminoethyl diphenylborinate (2-APB) in rats exposed to acoustic trauma (AT). Light microscopic, transmission electron microscopic ...