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Toplam kayıt 9, listelenen: 1-9
Cytotoxic, anti-proliferative and apoptotic effects of silver nitrate against H-ras transformed 5RP7
(Springer, 2016)
Metal based drugs have successfully been used in both the detection and treatment of different disease states. The antibacterial features of metal ion silver are well documented. Most recently, metal ion silver has been ...
Melatonin induces antiproliferative activity through modulation of apoptotic pathway in H-ras oncogene transformed 5RP7 cells
(Tubitak Scientific & Technical Research Council Turkey, 2015)
In the present study, cytotoxic and apoptotic effects of melatonin were investigated on H-ras oncogene transformed rat embryo fibroblast 5RP7 cells. Melatonin inhibited cell growth and induced apoptosis in 5RP7 cells. We ...
The apoptotic and genomic studies on A549 cell line induced by silver nitrate
(SAGE Publications LTD, 2017)
Lung cancer is the leading cause of male cancer deaths worldwide. Metal-based anticancer drugs have evolved significantly during the past decades. Recently, silver ions have been investigated for their anticancer effects. ...
Evaluation of Effects of Quercetin (3, 3 ', 4 ', 5, 7-pentohidroxyflavon) on Apoptosis and Telomerase Enzyme Activity in MCF-7 and NIH-3T3 Cell Lines Compared with Tamoxifen
(Aves Yayıncılık, 2011)
Objective: Quercetin has been shown to inhibit the proliferation of cancer cells. Tamoxifen is used for breast cancer. In this study, we have aimed to investigate the effects of quercetin and tamoxifen on telomerase enzyme ...
Niclosamide Suppresses Proliferation, Induces Apoptosis and Inhibits Wnt/beta-catenin Signaling Pathway in Human Ovarian Cancer Cells
(Gazi University, Fac Med, 2019)
Objective: The aim of this study is to investigate in vitro effects of an antihelminthic drug niclosamide on human ovarian carcinoma cell line OVCAR3. Methods: MTT assay was applied to investigate the cytotoxic effects of ...
Interaction of cancer cells with magnetic nanoparticles modified by methacrylamido-folic acid
(Dove Medical Press LTD, 2011)
Background: Magnetic nanoparticles show great promise for use as tools in a wide variety of biomedical applications. The purpose of this study was to investigate the potential effects of methacrylamido-folic acid ...
Studies on the cytotoxic, apoptotic and antitumoral effects of Au(III) and Pt(II) complexes of 1, 10-phenanthroline on V79 379A and A549 cell lines
(Informa Healthcare, 2012)
In the present study, Au(III) and Pt(II) complexes of 1, 10-phenanthroline (phen) were synthesized and used as the test compounds. The structure elucidation of the synthesized compounds was performed by IR, H-1-NMR and ...
Cytotoxic and apoptotic effects of ceranib-2 offering potential for a new antineoplastic agent in the treatment of cancer cells
(Tubitak Scientific & Technical Research Council Turkey, 2014)
Fibrocarcinomas are malignant tumours that originate in mesenchymal cells. The tumours typically form in the presence of connective tissue and are of key consideration when assessing research priorities for future healthcare ...
Inhibitory effects of salicylic acid on A549 human lung adenocarcinoma cell viability
(Tubitak Scientific & Technical Research Council Turkey, 2015)
Antiinflammatory drugs, such as salicylic acid and its metabolite acetylsalicylic acid, have been singled out as apoptosis-inducing agents with antitumoral activity. In addition, they reduce the risk of some cancers via ...