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dc.contributor.authorSidir, Yadigar Gülseven
dc.contributor.authorSidir, İsa
dc.contributor.authorBerber, Halil
dc.contributor.authorTasal, Erol
dc.contributor.authorÖğretir, Cemil
dc.date.accessioned2019-10-20T09:02:57Z
dc.date.available2019-10-20T09:02:57Z
dc.date.issued2010
dc.identifier.issn0021-9568
dc.identifier.urihttps://dx.doi.org/10.1021/je100378t
dc.identifier.urihttps://hdl.handle.net/11421/16577
dc.descriptionWOS: 000284017600028en_US
dc.description.abstractThe acid dissociation constants, as pK(a) values, of eight drug precursor 6-acylbenzothiazolon derivatives were determined using UV-vis spectroscopic technique. The protonation and deprotonation behaviors of the investigated molecules were studied from super basic to super acid regions (i.e., 8 mol.L-1 KOH to 98 % H2SO4) including the pH region. It was observed that protonation occurs only at the amid group in the super acid region. By validating the obtained acid dissociation constants, elucidation of the structure and protonation mechanisms of the studied molecules was attempted.en_US
dc.description.sponsorshipTurkish Scientific Council (TUBITAK) [108T192]en_US
dc.description.sponsorshipReceived for review April 19, 2010. Accepted June 11, 2010. We are grateful to Turkish Scientific Council (TUBITAK) for the financial support to this work via the Research Project with the number of 108T192.en_US
dc.language.isoengen_US
dc.publisherAmerican Chemical Societyen_US
dc.relation.isversionof10.1021/je100378ten_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.titleSpectroscopic Determination of Acid Dissociation Constants of Some Novel Drug Precursor 6-Acylbenzothiazolon Derivativesen_US
dc.typearticleen_US
dc.relation.journalJournal of Chemical and Engineering Dataen_US
dc.contributor.departmentAnadolu Üniversitesi, Fen Fakültesi, Fizik Bölümüen_US
dc.identifier.volume55en_US
dc.identifier.issue11en_US
dc.identifier.startpage4752en_US
dc.identifier.endpage4756en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.contributor.institutionauthorBerber, Halil


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