Advanced Search

Show simple item record

dc.contributor.authorSay, Rıdvan
dc.contributor.authorBiçen, Özlem
dc.contributor.authorYılmaz, Filiz
dc.contributor.authorHür, Deniz
dc.contributor.authorÖziç, Rasime
dc.contributor.authorDenizli, Adil
dc.contributor.authorErsöz, Arzu
dc.date.accessioned2019-10-20T09:13:48Z
dc.date.available2019-10-20T09:13:48Z
dc.date.issued2012
dc.identifier.issn0021-8995
dc.identifier.urihttps://dx.doi.org/10.1002/app.35376
dc.identifier.urihttps://hdl.handle.net/11421/17064
dc.descriptionWOS: 000302349700019en_US
dc.description.abstractLysozyme (Lys), also known as muramidase or N-acetylmuramide glycanhydrolase, is a family of enzymes that damage bacterial cell walls by catalyzing the hydrolysis of 1,4-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins. In this study, Lys was enhanced with a photosensitive facility by ruthenium chelate based monomers with a photosensitization and conjugation approach [amino acid (monomer) decorated and light underpinning conjugation approach]. Then, photosensitive Lys was allowed to interact with methacryloyl amido tyrosine (MATyr) monomer, which included tyrosine parts in its structure similar to those in the Lys structure. Two different types of cryogels including LysMATyr in their macropores were synthesized, LysMATyr cryogel and LysMATyrclay cryogel. These two materials were used for the measurement of the antibacterial activity on Gram-positive and Gram-negative bacteria. The effects of the modified Lys on Staphylococcus aureus and Micrococcus luteus were determined with a dilution plate method. The effects on Escherichia coli and S. aureus were determined with a turbidity method. According to the data, the LysMATyrclay modified embedded cryogel was effective on Gram-positive bacteria, and the LysMATyr modified embedded cryogel was so effective on Gram-negative bacteriaen_US
dc.language.isoengen_US
dc.publisherWiley-Blackwellen_US
dc.relation.isversionof10.1002/app.35376en_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectBiomaterialsen_US
dc.subjectConjugated Polymersen_US
dc.subjectEnzymesen_US
dc.titleNovel protein photocrosslinking and cryopolymerization method for cryogel-based antibacterial material synthesisen_US
dc.typearticleen_US
dc.relation.journalJournal of Applied Polymer Scienceen_US
dc.contributor.departmentAnadolu Üniversitesi, Fen Fakültesi, Fizik Bölümüen_US
dc.identifier.volume125en_US
dc.identifier.issue1en_US
dc.identifier.startpage145en_US
dc.identifier.endpage151en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.contributor.institutionauthorSay, Rıdvan
dc.contributor.institutionauthorYılmaz, Filiz
dc.contributor.institutionauthorHür, Deniz
dc.contributor.institutionauthorErsöz, Arzu


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record