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dc.contributor.authorŞener, gülsu
dc.contributor.authorÖzgür, Erdoğan
dc.contributor.authorYılmaz, Erkut
dc.contributor.authorUzun, Lokman
dc.contributor.authorSay, Rıdvan
dc.contributor.authorDenizli, Adil
dc.date.accessioned2019-10-20T09:13:50Z
dc.date.available2019-10-20T09:13:50Z
dc.date.issued2010
dc.identifier.issn0956-5663
dc.identifier.issn1873-4235
dc.identifier.urihttps://dx.doi.org/10.1016/j.bios.2010.06.003
dc.identifier.urihttps://hdl.handle.net/11421/17074
dc.descriptionWOS: 000283804400082en_US
dc.descriptionPubMed ID: 20605089en_US
dc.description.abstractThe aim of this study is to prepare quartz crystal microbalance (QCM) nanosensor for the real-time detection of lysozyme. In the first part, the lysozyme imprinted (MIP) nanoparticles were prepared by mini-emulsion polymerization. The MIP nanoparticles were characterized by TEM, zeta-sizer and FTIR-ATR measurements. Particle size was found around 50 nm. The MIP nanoparticles were attached by dropping of nanoparticle solution to gold surface and then, dried at 37 degrees C for 6 h. QCM nanosensor was characterized with AFM and ellipsometer. The observations indicated that the nanoparticle film was almost monolayer. The detection limit was found as 1.2 ng/mL. The specificity of the QCM nanosensor was shown by using albumin as a competitor molecule. The results show that the QCM nanosensor has high selectivity and sensitivity with a wide range of lysozyme concentrations in both aqueous solutions (0.2-1500 mu g/mL) and natural sources (egg white) (460-1500 ng/mL)en_US
dc.language.isoengen_US
dc.publisherElsevier Advanced Technologyen_US
dc.relation.isversionof10.1016/j.bios.2010.06.003en_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectQcmen_US
dc.subjectNanoparticlesen_US
dc.subjectLysozymeen_US
dc.subjectMolecular Imprintingen_US
dc.subjectNanosensorsen_US
dc.titleQuartz crystal microbalance based nanosensor for lysozyme detection with lysozyme imprinted nanoparticlesen_US
dc.typearticleen_US
dc.relation.journalBiosensors & Bioelectronicsen_US
dc.contributor.departmentAnadolu Üniversitesi, Fen Fakültesi, Fizik Bölümüen_US
dc.identifier.volume26en_US
dc.identifier.issue2en_US
dc.identifier.startpage815en_US
dc.identifier.endpage821en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.contributor.institutionauthorSay, Rıdvan


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