Bölüm "Anadolu Üniversitesi, Eczacılık Fakültesi, Farmakoloji Anabilim Dalı" Eczacılık Fakültesi için listeleme
Toplam kayıt 176, listelenen: 21-40
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Antinociceptive effect of methanol extract of Capparis ovata in mice
(Taylor & Francis LTD, 2010)Context: Capparis ovata Desf. (Capparaceae) grows widely in Turkey. Flower buds and fruits of the plant are used in folk medicine for their analgesic, antirheumatismal, and diuretic effects. Objective:This study evaluated ... -
Antinociceptive, antiinflammatory, and antioxidant activities of the ethanol extract of Crataegus orientalis leaves
(Tubitak Scientific & Technical Research Council Turkey, 2012)Aim: To determine the in vitro antioxidant activity and to investigate the possible antinociceptive and antiinflammatory effects of the ethanol extract of Crataegus orientalis leaves. The medicinal use of extracts prepared ... -
The Antioxidant Potency of Punica granatum L. Fruit Peel Reduces Cell Proliferation and Induces Apoptosis on Breast Cancer
(Mary Ann Liebert Inc, 2011)Pomegranate (Punica granatum L.) is known to possess pharmacological activities, such as antioxidant and anticancer. In this study, we evaluated the antioxidant potency of a methanolic pomegranate fruit peel extract (PPE) ... -
Antioxidant, Antiproliferative and Apoptotic Effects of Secondary Metabolites of Halotolerant Aspergillus terreus on Colon Adenocarcinoma Caco-2 Cells
(Asian Network Scientific Information-Ansinet, 2017)Objective: This study aimed to investigate the antioxidant and anticancer effects of the secondary metabolites of halotolerant Aspergillus terreus-2 (hAt-2) on colon adenocarcinoma (Caco-2) cells. The hAt-2 was isolated ... -
Antiproliferative and Apoptotic effects of Aprepitant on Human Glioblastoma U87MG Cells
(Marmara University, Fac Pharmacy, 2017)Glioblastoma multiforme, is the most malignant glioma among other gliomas with high incidence. It has aggresive properties such as high proliferation, invasion and migration rates. Therefore, recently studies have focused ... -
Antithrombotic effects of ethanol extract of Crataegus orientalis in the carrageenan-induced mice tail thrombosis model
(Pergamon-Elsevier Science LTD, 2011)Introduction: Crataegus species (common name is Hawthorn) are medicinal plants, which have flavonoids, triterpene acids, proanthocyanidins, and organic acids as main constituents, used in the treatment of cardiovascular ... -
Attenuation of ethanol withdrawal syndrome by extract of Hypericum perforatum in Wistar rats
(2006)The effects of Hypericum perforatum (St John's wort) on ethanol withdrawal syndrome have been investigated in ethanol-dependent rats. Adult male Wistar rats were subjects. Ethanol (7.2% v/v) was given to rats by a liquid ... -
Basal and histamine-induced gastric acid secretion in alloxan diabetic rats
(1993)1. 1. Effects of alloxan-induced diabetes on the rat gastric acid secretion were investigated using a number of biostatistical models described earlier. 2. 2. Histamine-induced gastric acid secretion was found to be decreased ... -
Beneficial effect of insulin on the decreased gastrointestinal ß-adrenergic responses in streptozotocin-diabetic rats: A contributing role of protein biosynthesis
(1992)The beneficial effect of insulin on the decreased gastrointestinal ß-adrenergic responses in experimentally diabetic rats has been reported. The effects of streptozotocin-induced diabetes and insulin on the isolated rat ... -
Beneficial effect of mirtazapine on diabetes-induced hyperalgesia: involvement of TRPV1 and ASIC1 channels in the spinal cord and dorsal root ganglion
(Taylor & Francis LTD, 2019)Objectives: Neuropathic pain reduces the life qualities of patients with Diabetes mellitus. Clinical guidelines recommend relief in diabetic neuropathic pain through the use of some antidepressants, anticonvulsants, opioids ... -
A benzothiazole/piperazine derivative with acetylcholinesterase inhibitory activity: Improvement in streptozotocin-induced cognitive deficits in rats
(Polish Acad Sciences Inst Pharmacology, 2017)Background: Acetylcholinesterase (AChE) inhibitors are frequently prescribed to mitigate the cognitive decline in Alzheimer's disease. Thus, we investigated the possible efficacy of the AChE inhibitor 2-[(6-Nitro-2-benzothiazolyl) ... -
Calmodulin content and in vitro contractility of duodenum from streptozotocin-induced diabetic rats: Effects of insulin therapy and calmodulin antagonism
(Elsevier Science BV, 1997)The effects of experimental diabetes and insulin treatment on the decreased reactivity of isolated rat duodenum to KCI and calmidazolium, a specific calmodulin antagonist, were examined. After 8 weeks of streptozotocin ... -
Camellia sinensis increased apoptosis on U2OS osteosarcoma cells and wound healing potential on NIH3T3 fibroblast cells
(Springer, 2017)Camellia sinensis (Cs) is a plant which is rich in polyphenols and has antioxidant, antiinflammatory, antimutagenic, anticarcinogenic and antibacterial activities. In this study, two different methanol extracts (Cs-I and ... -
Central Nervous System Activities of Hypericum origanifolium Extract via GABAergic and Opioidergic Mechanisms
(Wiley, 2013)Pharmacological effects of hydroalcoholic extract prepared from Hypericum origanifolium Willd. (Guttiferae) on behavioral parameters and pain perceptions of mice were investigated in this study. Depression, anxiety, ... -
Central nervous system activity of 2-(Naphthalen-1-yl)-4, 5-dimethyl-(1H)-imidazole(NDI)
(Blackwell Publishing, 2006)… -
The Centrally-Mediated Mechanisms of Action of Ferulic Acid-Induced Antinociception
(Marmara University, Fac Medicine, 2016)This study aimed to investigate the central antinociceptive effects of ferulic acid, a common phenolic compound found in various medicinal plants used for pain relief, and the contribution of cholinergic, serotonergic, ... -
Chronic heavy ethanol consumption is associated with decreased platelet aggregation in rats
(Tohoku University Medical Press, 2005)Although moderate alcohol consumption seems to be protective against atherosclerosis, coronary artery disease rate increases with its higher doses. Platelet aggregation is an important process which contributes to the ... -
Comparative Studies on Phenolic Composition, Antioxidant, Wound Healing and Cytotoxic Activities of Selected Achillea L. Species Growing in Turkey
(MDPI AG, 2015)Turkey is one of the most important centers of diversity for the genus Achillea L. in the world. Keeping in mind the immense medicinal importance of phenols, in this study, three species growing in Turkey, A. coarctata ... -
Comparison of antiproliferative and apoptotic effects of a novel proteasome inhibitor MLN2238 with bortezomib on K562 chronic myeloid leukemia cells
(Taylor & Francis LTD, 2016)Inhibition of the proteasome has emerged as a clinically effective anticancer therapeutic approach in recent years. Bortezomib (Velcade (R)) showed extremely high potency against a wide range of cancer cell lines. Ixazomib ...