Kurum Yazarı "Karaburun, Ahmet Çağrı" Eczacılık Fakültesi İçin Listeleme
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New chroman-4-one/thiochroman-4-one derivatives as potential anticancer agents
Demirayak, Şeref; Yurttaş, Leyla; Gündoğdu-Karaburun, Nalan; Karaburun, Ahmet Çağrı; Kayagil, İsmail (Elsevier Science BV, 2017)The synthesis of 3-[3/4-(2-aryl-2-oxoethoxy) arylidene] chroman/thiochroman-4-one derivatives (1-34) and evaluation of their anticancer activities were aimed in this work. Final compounds were obtained in multistep synthesis ... -
Some 1-substituted 3-aryl-1,4-dihydro-1,2,4-triazino[4,3-a]- benzimidazoles and their vasodilatory activities
Demirayak, Şeref; Benkli, Kadriye; Karaburun, Ahmet Çağrı (Societa Chimica Italiana, 1997)In this study, some 1-substituted 3-aryl-1,4-dihydro-1,2,4- triazino[4,3-a]benzimidazole derivatives were synthesized, their structures were elucidated, and their vasodilatory activities were examined. It was found that ... -
Some pyridazinone and phthalazinone derivatives and their vasodilator activities
Demirayak, Şeref; Karaburun, Ahmet Çağrı; Kayagil, İsmail; Erol, K.; Sırmagül, Başar (Pharmaceutical Society of Korea, 2004)In this study, 6-[(4-arylidene-2-phenyl-5-oxoimidazolin-1-yl)phenyl]-4,5- dihydro-3(2H)-pyridazinone and 4-[(4-arylidene-2-phenyl-5-oxoimidazolin-1-yl) phenyl]-1(2H)-phthalazinone derivatives were synthesized by reacting ... -
Some pyrrole substituted aryl pyridazinone and phthalazinone derivatives and their antihypertensive activities
In this work, some 2-nonsubstituted/2-methyl-/2-(2-acetyloxyethyl)-6-[4- (substituted pyrrol-1-yl)phenyl]-4,5-dihydro-3(2H)-pyridazinone, derivatives and 2-nonsubstituted/2-methyl- 4-[4-(substituted pyrrol-1-yl)phenyl]-1(2H)- ... -
Some thiazolylaminopyrrole derivatives and their antimicrobial activity
In this study, some ethyl 1-(4-arylthiazol-2-yl)amino-2-methyl-5-aryl-1H-pyrrole-3-carboxylic acid derivatives were obtained by reacting 1-(2-methyl-3-carbethoxy-5-arylpyrrol-1-yl)thioureas with ?-bromoacetophenone ... -
Synthesis and anti-cancer activity evaluation of new aurone derivatives
Demirayak, Şeref; Yurttaş, Leyla; Gündoğdu-Karaburun, Nalan; Karaburun, Ahmet Çağrı; Kayagil, İsmail (Taylor & Francis LTD, 2015)In this study, we have synthesized 2-[3-or 4-(2-aryl-2-oxoethoxy) arylidene] benzofuran-3-one derivatives (D1-D38) and evaluated their anti-cancer activities. The final compounds were obtained in multistep synthesis reactions ... -
Synthesis and antibacterial activities of some 1-[2-(substituted pyrrol- 1-yl)ethyl]-2-methyl-5-nitroimidazole derivatives
Demirayak, Şeref; Karaburun, Ahmet Çağrı; Kiraz, N. (Elsevier Masson SAS, 1999)In this study, some 1-[2-(substituted pyrrol-1-yl)ethyl]-2-methyl-5- nitroimidazole derivatives were synthesized by reacting 2-(2-methyl-5-nitro- 1H-imidazolyl)ethylamine dihydrochloride, which was prepared using metronidazole, ... -
Synthesis and antibacterial and antifungal evolution of some ethyl 1- aryloxyacetylamino-5-arylpyrrole-3-carboxylic acid derivatives
In this study some ethyl 1-aryloxyacetylamino-2methyl-5-aryl-1H-pyrrole- 3-carboxylic acid derivatives were obtained by reacting some aryloxyacetylhydrazide and 1-aryl-3-carbethoxy-1,4-pentadione derivatives. The antibacterial ... -
Synthesis and Anticancer Activity of Some 1H-inden-1-one Substituted (Heteroaryl)Acetamide Derivatives
Karaburun, Ahmet Çağrı; Gündoğdu-Karaburun, Nalan; Yurttaş, Leyla; Kayagil, İsmail; Demirayak, Şeref (Bentham Science Publ LTD, 2019)Background: The synthesis of 2-[3/4-((6-substituted-1-oxo-2,3-dihydro-1H-inden-2ylidene) methyl)phenoxy]-N-(heteroaryl)acetamide derivatives and the investigation of their anticancer activity were studied. Methods: ... -
Synthesis and Anticancer Activity of Some 2-[3/4-(2-Substituted Phenyl-2-oxoethoxy)benzylidene]-6-substituted-2,3-dihydro-1H-inden-1-one Derivatives
Gündoğdu-Karaburun, Nalan; Karaburun, Ahmet Çağrı; Demirayak, Şeref; Kayagil, İsmail; Yurttaş, Leyla (Bentham Science Publ LTD, 2014)The synthesis of 2-[3/ 4-(2-substituted phenyl-2-oxoethoxy) benzylidene]-6-substituted-2,3-dihydro-1H-inden-1one derivatives and the investigation of their anticancer activity were studied. 2-(3- or 4-Hydroxybenzylidene) ... -
Synthesis and Anticandidal Activities of Some Aryl (5-Chloro-Benzofuran-2-yl) Ketoximes
Karaburun, Ahmet Çağrı (Bentham Science Publ LTD, 2019)Background: In this study, some aryl (5-chloro-benzofuran-2-yl) ketoximes and their ethers were synthesised to evaluate their antifungal activity against C. albicans, C. glabrata, C. krusei, and C. parapsilosis. Methods: ... -
Synthesis and antifungal activities of some aryl (3-methyl-benzofuran-2-yl) ketoximes
Benkli, Kadriye; Gündoğdu-Karaburun, N; Karaburun, Ahmet Çağrı; Uçucu, Ümit; Demirayak, Şeref; Kiraz, N (Pharmaceutical Society Korea, 2003)In this study, some aryl (3-methyl-benzofuran-2-yl) ketoximes and their. ethers and esters were synthesised. The structure elucidation of the compounds was performed by IR, H-1-NMR, MASS spectroscopy and elemental analyses. ... -
Synthesis and Antifungal Activities of Some Aryl Naphthofuran Ketoximes
Karaburun, Ahmet Çağrı; Gündoğdu-Karaburun, Nalan; Uçucu, Ümit; Demirayak, Şeref (Bentham Science Publ LTD, 2011)In this study, some aryl naphtho[2,1-b] furan-2-yl ketoximes and their ethers and esters were synthesised. The structure elucidation of the compounds was performed by IR, H-1-NMR and MASS spectroscopic data and elemental ... -
Synthesis and antifungal activities of some aryl(benzofuran-2-yl)ketoximes
Demirayak, Şeref; Uçucu, Ümit; Benkli, Kadriye; Gündoğdu-Karaburun, Nalan; Karaburun, Ahmet Çağrı; Akar, D; Kiraz, N (Elsevier Science Sa, 2002)In this study, some aryl(benzofuran-2-yl)ketoximes and their ethers and esters were synthesised. The structure elucidation of the compounds was performed by IR, H-1 NMR and mass spectroscopic data and elemental analyses ... -
Synthesis and Antifungal Potential of Some Novel Benzimidazole-1,3,4-Oxadiazole Compounds
Karaburun, Ahmet Çağrı; Kaya Çavuşoğlu, Betül; Çevik, Ulviye Acar; Osmaniye, Derya; Sağlık, Begüm Nurpelin; Levent, Serkan; Kaplancıklı, Zafer Asım (MDPI, 2019)Discovery of novel anticandidal agents with clarified mechanisms of action, could be a rationalist approach against diverse pathogenic fungal strains due to the rise of resistance to existing drugs. In support to this ... -
Synthesis and Antiproliferative Activity of 2-arylidene 6-(2-aryl-2-oxoethoxy) Benzofuran-3-one Derivatives
Demirayak, Şeref; Yurttaş, Leyla; Karaburun, Ahmet Çağrı; Gündoğdu-Karaburun, Nalan; Kayagil, İsmail (Bentham Science Publ LTD, 2016)The synthesis of 2-arylidene 6-(2-aryl-2-oxoethoxy) benzofuran-3-one derivatives was reported and selected compounds were determined for their anticancer activity evaluation in National Cancer Institute NCI, USA according ... -
Synthesis and cytotoxic and analgesic activities of some 1, 5-diaryl-3-ethoxycarbonylpyrrole derivatives
Demirayak, Şeref; Arslan, Rana; Karaburun, Ahmet Çağrı; Kayagil, İsmail; Seller, Zerrin; Uçucu, Ümit (2006)Some 1,5-diaryl-3-ethoxycarbonyl-2-methylpyrrole derivatives were obtained by reacting 1-aryl-3-ethoxycarbonylpent-1,4-diones and a suitable aniline derivative or sulfanilamide under Paal-Knorr pyrrole synthesis conditions. ... -
Synthesis and Evaluation of New 1,3,4-Thiadiazole Derivatives as Potent Antifungal Agents
Karaburun, Ahmet Çağrı; Çevik, Ulviye Acar; Osmaniye, Derya; Sağlık, Begüm Nurpelin; Kaya Çavuşoğlu, Betül; Levent, Serkan; Kaplancıklı, Zafer Asım (MDPI, 2018)With the goal of obtaining a novel bioactive compound with significant antifungal activity, a series of 1,3,4-thiadiazole derivatives (3a-3l) were synthesized and characterized. Due to thione-thiol tautomerism in the ... -
Synthesis, Antibacterial and Antifungal Activities of Some Carbazole Dithiocarbamate Derivatives
Karaburun, Ahmet Çağrı; Kaplancıklı, Zafer Asım; Gündoğdu-Karaburun, Nalan; Demirci, Fatih (Bentham Science Publ LTD, 2011)In this study, we aimed at the synthesis of new N, N-disubstituted dithiocarbamoic acid, 2-[(9-ethyl-9H-carbazol-3-yl) amino]-2-oxoethyl esters and their antimicrobial evaluations. The chemical structures of the compounds ...