Kurum Yazarı "Kuş, Gökhan" Eczacılık Fakültesi İçin Listeleme
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Critical Role of Astrocytes on Striatal Neuro-Chemistry in Vip Treated Parkinsonian Rats
Tuncel, N.; Yelkenli, I; Ulupınar, E.; Korkmaz, O. T.; Şener, E.; Kuş, Gökhan (Humana Press Inc, 2013)… -
Indomethacin based new triazolothiadiazine derivatives: Synthesis, evaluation of their anticancer effects on T98 human glioma cell line related to COX-2 inhibition and docking studies
Sever, Belgin; Altıntop, Mehlika Dilek; Kuş, Gökhan; Özkurt, Mete; Özdemir, Ahmet; Kaplancıklı, Zafer Asım (Elsevier France-Editions Scientifiques Medicales Elsevier, 2016)In the current work, new 1,2,4-triazolo[3,4-b]-1,3,4-thiadiazine derivatives (1-8) were synthesized via the ring closure reaction of 2-bromoacetophenone derivatives with 4-amino-5-[(5-methoxy-2-methyl-1(4-chlorobenzoyl)- ... -
Modulation of Corpus Striatal Neurochemistry by Astrocytes and Vasoactive Intestinal Peptide (VIP) in Parkinsonian Rats
Yelkenli, İbrahim Halil; Ulupınar, Emel; Korkmaz, Orhan Tansel; Şener, Erol; Kuş, Gökhan; Filiz, Zeynep; Tuncel, Neşe (Humana Press Inc, 2016)The neurotoxin 6-hydroxydopamine (6-OHDA) is widely used in animal models of Parkinson's disease. In various neurodegenerative diseases, astrocytes play direct, active, and critical roles inmediating neuronal survival and ... -
Synthesis and evaluation of naphthalene-based thiosemicarbazone derivatives as new anticancer agents against LNCaP prostate cancer cells
Altıntop, Mehlika Dilek; Sever, Belgin; Özdemir, Ahmet; Kuş, Gökhan; Öztopçu-Vatan, Pınar; Kabadere, Selda; Kaplancıklı, Zafer Asım (Taylor & Francis LTD, 2016)Fourteen new naphthalene-based thiosemicarbazone derivatives were designed as anticancer agents against LNCaP human prostate cancer cells and synthesized. MTT assay indicated that compounds 6, 8 and 11 exhibited inhibitory ...