Kurum Yazarı "Koparal, Ayşe Tansu" Fen Fakültesi İçin Listeleme
-
Differential effect of green tea catechins on three endothelial cell clones isolated from rat adipose tissue and on human umbilical vein endothelial cells
Koparal, Ayşe Tansu; Yamaguchi, H; Omae, K; Torii, S; Kitagawa, Y (Springer, 2004)By single colony isolation from the cells in stromal vascular fraction (SVF) dispersed from rat adipose tissues, we isolated three independent clones with different proliferation potential. All clones showed cobblestone-like ... -
Effects of carvacrol on a human non-small cell lung cancer (NSCLC) cell line, A549
Koparal, Ayşe Tansu; Zeytinoğlu, Melih (Springer, 2003)Carvacrol, the predominant monoterpene in many essential oils of Labitae including Origanum, Satureja, Thymbra, Thymus, and Corydothymus has substantial antibacterial, anti fungal, antihelmintic, insecticial, analgesic and ... -
Evaluation of Multifunctional Hybrid Analogs for Stilbenes, Chalcones and Flavanones
Çağır, Ali; Odaci, Burcu; Varol, Mehmet; Akcok, İsmail; Okur, Özgür; Koparal, Ayşe Tansu (Bentham Science Publ LTD, 2017)Aims: In this study, discovery of novel anticancer agents acting by more than one mechanism was aimed. Method: For this purpose, eleven previously synthesized simple-stilbene, chalcone, flavanone derivatives and 31 novel ... -
Evaluation of the Angiogenic Activity of Salvia triloba L. Essential Oil
Koparal, Ayşe Tansu; Demirci, Betül; Kaya, M.; Duali, G.; Butun, S.; Başer, K. Hüsnü Can; Demirci, Fatih (Georg Thieme Verlag Kg, 2009)… -
Evaluation of the sunscreen lichen substances usnic acid and atranorin
Varol, Mehmet; Tay, Turgay; Candan, Mehmet; Türk, Ayşen Özdemir; Koparal, Ayşe Tansu (Inst Histol Embriol-Conicet, 2015)Usnic acid and atranorin are known as both sunscreen substances in natural lichen population and cytotoxic substances on human cell lines. Both substances were isolated from the acetone extracts of Cladonia foliacea and ... -
Expression of Vegf Gene in Ovcar-3 Cells After Exposed to Epigallocatechin-3-Gallate and Paclitaxel Combination
Eskin, N.; Bostancıoğlu, Rakibe Beklem; Koparal, Ayşe Tansu; Özalp, S. Sinan (Lippincott Williams & Wilkins, 2013)… -
Gold(III) compounds-mediated inhibition of lung cancer cell proliferation
Bostancıoğlu, R. Beklem; Kaya, Murat; Koparal, Ayşe Tansu; Benkli, Kadriye (Lippincott Williams & Wilkins, 2016)Research on chemotherapeutics for lung cancer is crucial for designing a new therapeutic strategy against malignant lung tumors. Although radiotherapy and chemotherapy, which are not selective for cancer cells and exert ... -
The in vitro assessment of dipyridophenazine complexes in H-ras oncogene transformed rat embryo fibroblast 5RP7 cell line
Kaplan, Ayşe; Benkli, Kadriye; Koparal, Ayşe Tansu (Springer, 2018)Purpose The aim of this study is to detect apoptotic and cytotoxic/antiproliferative effects of a ligand substance and its metal derivatives. The substances were investigated by using an h-ras oncogene transformed rat ... -
In vitro evaluation of combination of EGCG and Erlotinib with classical chemotherapeutics on JAR cells
Telli, Elçin; Genç, Hatice; Tasa, Burcugül Altuğ; Özalp, S. Sinan; Koparal, Ayşe Tansu (Springer, 2017)Gestational Trophoblastic Neoplasia (GTN) is a term used for a group of malignant gynecological tumors including choriocarcinoma. Low-risk neoplasias can be cured using single agents Methotrexate (MTX) and actinomycin-D(ACD), ... -
Induction of apoptosis and inhibition of cell proliferation by the cyclooxgenase enzyme blocker nimesulide in the Ishikawa endometrial cancer cell line
Özalp, S. Sinan; Eren, Ceren Yıldız; Bostancıoğlu, Rakibe Beklem; Koparal, Ayşe Tansu (Elsevier Science BV, 2012)Objectives: Endometrial cancer remains a leading cause of death in women and therefore the development of new therapies is essential. The present study evaluated the effects of nimesulide alone, cisplatin alone, and ... -
Investigation of the pharmacological profiles of dinuclear metal complexes as novel, potent and selective cytotoxic agents against leas-transformed cells
Bostancıoğlu, R. Beklem; Koparal, Ayşe Tansu; Benkli, Kadriye (Elsevier Science BV, 2014)Around the world scientists try to design successful cures against still incurable diseases, especially cancers. New targets for prevention and new agents for therapy need to be identified. We synthesized novel metal ... -
Novel ferrocenyl-containing N-acetyl-2-pyrazolines inhibit in vitro angiogenesis and human lung cancer growth by interfering with F-actin stress fiber polimeryzation
Bostancıoğlu, R. Beklem; Demirel, Seda; Cin, Gunseli Turgut; Koparal, Ayşe Tansu (Taylor & Francis LTD, 2013)Cancer is a significant worldwide health problem generally because of lack of widespread and comprehensive early detection methods. Lung cancer is the leading cause of cancer deaths in men worldwide and the second leading ... -
Photoprotective Activity of Vulpinic and Gyrophoric Acids Toward Ultraviolet B-Induced Damage in Human Keratinocytes
Varol, Mehmet; Türk, Ayşen Özdemir; Candan, Mehmet; Tay, Turgay; Koparal, Ayşe Tansu (Wiley, 2016)Vulpinic and gyrophoric acids are known as ultraviolet filters for natural lichen populations because of their chemical structures. However, to the best of our knowledge, there has been no reference to their cosmetic ... -
Promotion of Hair Growth by Traditionally Used Delphinium Staphisagria Seeds through Induction of Angiogenesis
Koparal, Ayşe Tansu; Bostancıoğlu, Rakibe Beklem (Shaheed Beheshti University, Sch Pharmacy, 2016)How the seeds of Delphinium staphisagria promote hair growth in humans is yet to be discovered. This lack of information leads us to the investigation of hair promoting effects of seeds of Delphinium staphisagria in-vitro. ... -
Promotion of hair growth by traditionally used Delphinium staphisagria seeds through induction of angiogenesis
Koparal, Ayşe Tansu; Bostancıoğlu, Rakibe Beklem (Iranian Journal of Pharmaceutical Research, 2016)How the seeds of Delphinium staphisagria promote hair growth in humans is yet to be discovered. This lack of information leads us to the investigation of hair promoting effects of seeds of Delphinium staphisagria in-vitro. ... -
Resveratrol reduces IL-6 and VEGF secretion from co-cultured A549 lung cancer cells and adipose-derived mesenchymal stem cells
Şahin, Erhan; Baycu, Cengiz; Koparal, Ayşe Tansu; Dönmez, Dilek Burukoğlu; Bektur, Ezgi (SAGE Publications LTD, 2016)Stem cell therapies are important treatment methodologies used in many areas of experimental or clinical medicine. In recent studies of cancer models, Mesenchymal stem cells (MSCs) suppressed the growth of cancer cells. ... -
Serous Intraepithelial Carcinoma of Endometrium and Tuba Uterina. Which One Is the Origin: a Case Report
Eskin, N.; Bostancıoğlu, Rakibe Beklem; Koparal, Ayşe Tansu; Özalp, S. Sinan (Lippincott Williams & Wilkins, 2013)… -
Studies on the cytotoxic, apoptotic and antitumoral effects of Au(III) and Pt(II) complexes of 1, 10-phenanthroline on V79 379A and A549 cell lines
Bostancıoğlu, R. Beklem; Işık, Kenan; Genç, Hatice; Benkli, Kadriye; Koparal, Ayşe Tansu (Informa Healthcare, 2012)In the present study, Au(III) and Pt(II) complexes of 1, 10-phenanthroline (phen) were synthesized and used as the test compounds. The structure elucidation of the synthesized compounds was performed by IR, H-1-NMR and ...