Yazar "Karaosmanoğlu, Oğuzhan" için Fen Fakültesi listeleme
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Cytotoxicity of 11 naturally occurring phenolics and terpenoids from Kenyan flora towards human carcinoma cells
Kuete, Victor; Omosa, Leonidah K.; Midiwo, J. O.; Karaosmanoğlu, Oğuzhan; Sivas, Hakan (Elsevier B.V., 2018)Background: Cancer constitutes a major hurdle worldwide and its treatment mainly relies on chemotherapy. Objectives: The present study was designed to evaluate the cytotoxicity of 11 naturally occurring compounds including ... -
Cytotoxicity of seputhecarpan D, thonningiol and 12 other phytochemicals from African flora towards human carcinoma cells
Kuete, Victor; Ngnintedo, Dominique; Fotso, Ghislain W.; Karaosmanoğlu, Oğuzhan; Ngadjui, Bonaventure T.; Keumedjio, Felix; Sivas, Hülya (Bmc, 2018)Background: Despite the remarkable progress in cancer therapy in recent years, this disease still remains a serious public health concern. The use of natural products has been and continues to be one of the most effective ... -
Cytotoxicity of the methanol extracts of Elephantopus mollis, Kalanchoe crenata and 4 other Cameroonian medicinal plants towards human carcinoma cells
Kuete, Victor; Fokou, Fabrice W.; Karaosmanoğlu, Oğuzhan; Beng, Veronique P.; Sivas, Hülya (Bmc, 2017)Background: Cancer still constitutes one of the major health concerns globally, causing serious threats on patients, their families, and the healthcare system. Methods: In this study, the cytotoxicity of the methanol extract ... -
Identification of biomarkers associated with partial epithelial to mesenchymal transition in the secretome of slug over-expressing hepatocellular carcinoma cells
Karaosmanoğlu, Oğuzhan; Banerjee, Sreeparna; Sivas, Hülya (Springer, 2018)Hepatocellular carcinoma (HCC) is the second leading cause of cancer-related deaths worldwide. Complete epithelial to mesenchymal transition (EMT) has long been considered as a crucial step for metastasis initiation. It ... -
In vitro cytotoxicity of compounds isolated from Desbordesia glaucescens against human carcinoma cell lines
Kuete, Victor; Mafodong, F. L. Dongmo; Çelik, I.; Fobofou, S. A. T.; Ndontsa, B. L.; Karaosmanoğlu, Oğuzhan; Sivas, Hülya (Elsevier Science BV, 2017)Malignancies constitute a global health concern and chemotherapy remains the main mode of treatment. The present study was designed to evaluate the cytotoxicity of 8 compounds from Desbordesia glaucescens namely ... -
Two new pterocarpans and a new pyrone derivative with cytotoxic activities from Ptycholobium contortum (NEBr.) Brummitt (Leguminosae): revised NMR assignment of mundulea lactone
Ngnintedo, Dominique; Fotso, Ghislain W.; Kuete, Victor; Nana, Frederic; Sandjo, Louis P.; Karaosmanoğlu, Oğuzhan; Andrae-Marobela, Kerstin (Springeropen, 2016)Background: Ptycholobium is a genus related to Tephrosia which comprises only three species. Compared to Tephrosia, which has been phytochemically and pharmacologically studied, Ptycholobium species have only few or no ...