Güncel Gönderiler: eArsiv@Anadolu: Anadolu University Institutional Repository
Toplam kayıt 26743, listelenen: 4261-4280
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An in vitro investigation of genotoxic effects of dexketoprofen trometamol on healthy human lymphocytes
(Taylor & Francis Ltd, 2020)Non-steroidal anti-inflammatory drugs are drugs with analgesic, antipyretic, and anti-inflammatory effects. This study uses in vitro methods to investigate the potential and unknown genotoxic effects of dexketoprofen ... -
Being the Father of a Child Who Is Deaf or Hard of Hearing: A Phenomenological Study of Fatherhood Perceptions and Lived Experiences in the Turkish Context
(Gallaudet Univ Press, 2020)The present study investigated the phenomenon of being a father of a child who is deaf or hard of hearing (DHH) and attending an early intervention service in the Turkish context. the research was designed as a transcendental ... -
Caffeoylquinic Acids, Cytotoxic, Antioxidant, Acetylcholinesterase and Tyrosinase Enzyme Inhibitory Activities of Six Inula Species from Bulgaria
(Wiley-V C H Verlag Gmbh, 2020)Chlorogenic (5-CQA), 1,5-, 3,5-, 4,5- and 3,4-dicaffeoylquinic (DCQA) acids were identified and quantified in the methanol extracts of Inula oculus-christi L., I. bifrons L., I. aschersoniana Janka var. aschersoniana, I. ... -
Synthesis and docking study of benzimidazole-triazolothiadiazine hybrids as aromatase inhibitors
(Wiley-V C H Verlag Gmbh, 2020)Aromatase is involved in the biosynthesis of estrogen and thus is a critical target for breast cancer. in this study, to identify new aromatase enzyme inhibitors, seven 3-[4-(5-methyl-1H-benzo[d]imidazol-2-yl)phenyl]-6-( ... -
Antimicrobial, anticholinesterase evaluation and chemical characterization of essential oil Phlomis kurdica Rech. fil. Growing in Turkey
(Taylor & Francis Inc, 2020)The Phlomis kurdica Rech.fil. (Lamiaceae) essential oil was investigated for its chemical constituents and in vitro biological activities. Volatile components were characterized, antimicrobial and anticholinesterase ... -
Calcium channel blockers: molecular docking and inhibition studies on carbonic anhydrase I and II isoenzymes
(Taylor & Francis Inc, 9999)Carbonic anhydrases (CAs) are potent dehydration of carbonic acid and catalyst of the reversible hydration of carbon dioxide. Here, CA I and CA II was purified from human erythrocytes using the simple chromatographic method ... -
Does disability matter in counselling? Views of counsellors with visual disabilities and their clients
(Routledge Journals, Taylor & Francis Ltd, 2020)In this study we investigated the case of disability from the perspective of counsellors with visual disability (CWVD) and their clients by focusing on the counselling skills of CWVD, the relationships with their clients, ... -
Development of self-care behaviours in counsellors-in-training through an experiential self-care course: an action research
(Routledge Journals, Taylor & Francis Ltd, 9999)The purpose of this study was to evaluate changes in the self-care behaviours of counsellors-in-training who participated in a 12-week experiential "Self-Care Course for Counsellors-SCC". the study was conducted through ... -
Carbonic anhydrase, obstructive sleep apnea and hypertension: Effects of intervention
(Wiley, 2020)Whole blood carbonic anhydrase activity (CAa) is increased in patients with obstructive sleep apnea (OSA). Our study investigated the influence of positive airway pressure (PAP) or CA inhibitor acetazolamide (ACT) therapy ... -
A novel lanthanide-chelate based molecularly imprinted cryogel for purification of hemoglobin from blood serum: An alternative method for thalassemia diagnosis
(Elsevier Sci Ltd, 2020)Purification and analyzing of proteins is an essential means for understanding their function and diseases associated with their lack or defect. in this research, a new lanthanide-chelate based molecularly imprinted polymer ... -
Physicochemical characterization and pharmacokinetic evaluation of rosuvastatin calcium incorporated solid lipid nanoparticles
(Elsevier, 2020)Rosuvastatin calcium (RCa) is a very efficient antihyperlipidemic agent, however, being a BCS class II drug, results in poor oral bioavailability. the present study focused on the enhancement of oral bioavailability of RCa ... -
Catecholaminergic and opioidergic system mediated effects of reboxetine on diabetic neuropathic pain
(Springer, 2020)Rationale Current data indicate that the noradrenergic system plays a critical role in neuropathic pain treatment. Notably, drugs that directly affect this system may have curative potential in neuropathy-associated pain. ... -
Emotional and social competence in the aestheticization of labor in the restaurant industry
(Emerald Group Publishing Ltd, 2020)Purpose the purpose of this paper is to provide guidance regarding the satisfaction of customer needs in the competitive restaurant industry. Restaurants have seen a transformation in employees' labor, changing from primarily ... -
Effect of different molecular weight PLGA on flurbiprofen nanoparticles: formulation, characterization, cytotoxicity, and in vivo anti-inflammatory effect by using HET-CAM assay
(Taylor & Francis Ltd, 2020)Objective: the effect of polymers used in nanoparticle (NP) production on the formulation properties is one of the few studied issues. Therefore, this study aims to formulate flurbiprofen (FLB) loaded NPs with different ... -
Sulfonamides incorporating ketene N,S-acetal bioisosteres as potent carbonic anhydrase and acetylcholinesterase inhibitors
(Wiley-V C H Verlag Gmbh, 2020)In this study, 15 novel compounds in a series of sulfonamide-based ketenes (7a-o) were synthesized and characterized using Fourier-transform infrared spectroscopy, nuclear magnetic resonance spectroscopy, and mass spectrometry. ... -
Screening of non-alkaloid acetylcholinesterase and carbonic anhydrase isoenzymes inhibitors of Leiotulus dasyanthus (K. Koch) Pimenov & Ostr. (Apiaceae)
(Taylor & Francis Inc, 2020)The oxidant, cholinesterase, and carbonic anhydrase inhibitions of essential oils and their major compounds of Leiotulus dasyanthus and molecular docking studies of alpha-pinene and (TM)-3-carene were evaluated in this ... -
Multifunctional quinoxaline-hydrazone derivatives with acetylcholinesterase and monoamine oxidases inhibitory activities as potential agents against Alzheimer's disease
(Springer Birkhauser, 2020)Multitarget molecules are considered as an effective way for the treatment of AD, instead of the classic one-drug-one-target strategy because of the multifactorial nature of AD. A variety of studies indicate that several ... -
Secondary metabolites from Verbascum bugulifolium Lam. and their bioactivities
(Taylor & Francis Ltd, 9999)Five iridoid glycosides catalpol (1), specioside (2), ajugol (3), ajugoside (4), 8-O-acetylharpagide (5), two phenylethanoid glycosides, verbascoside (6) and glucopyranosyl-(1 -> G(i)-6)-martynoside (7), four flavonoids, ... -
Synthesis of some novel 3,4,5-trisubstituted triazole derivatives bearing quinoline ring and evaluation of their antimicrobial activity
(Taylor & Francis Ltd, 9999)Some new 3,4,5-trisubstituted 1,2,4-triazole derivatives were synthesized and studied for their antimicrobial activity. the lead compounds were obtained starting from 8-hydroxyquinoline and ethyl 2-chloroacetate. the ... -
Economic growth and environmental degradation: evidence from the US case environmental Kuznets curve hypothesis with application of decomposition
(Routledge Journals, Taylor & Francis Ltd, 9999)This study re-tests the environmetal Kuznets curve (EKC) hypothesis for the US, based on a methodology that differentiates this study from previous empirical studies.To this aim, the per-capita income series (variable) is ...
