Browsing by Author "Öztürk, Ahmet Alper"
Now showing items 1-15 of 15
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Cefaclor monohydrate loaded microemulsion formulation for topical application: Characterization with new developed UPLC method and stability study
Öztürk, Ahmet Alper; Güven, Umay Merve (Marmara University, 2019)The purpose of this study was to formulate Cefaclor monohydrate (CEF) loaded microemulsion formulations with the help of pseudo-ternary phase diagrams for topical application. Additionally, in this study also a new ... -
Deksketoprofen trometamol yüklü kontrollü salım gösteren nanoboyutta ilaç taşıyıcı sistem geliştirilmesi ve in Vitro/in vivo değerlendirilmesi
Öztürk, Ahmet Alper (Anadolu Üniversitesi, 2017)Tarihin en eski ve üzerinde en fazla çalışılan ilaç araştırma konularından biri ilaç ile ağrı tedavisidir. Postoperatif ağrı ile hafif ve orta şiddetteki ağrıların tedavisinde analjezik etkili ilaç kullanımı tüm dünyada ... -
Development of nano-sized ketoprofen lysine incorporated Eudragit (R) S100 nanomedicine by double emulsion solvent evaporation and in vitro characterization
Öztürk, Ahmet Alper; Çınar, Nur İlge; Yenilmez, Evrim (Journal Pharmacy & Pharmacognosy Research-Jppres, 2019)Context: Pain has a very important effect on the biological, psychological, sociological and economic situation of a patient. Nanoparticles (NPs) are being extensively investigated as drug delivery systems worldwide for ... -
Dexketoprofen trometamol-loaded eudragit® rl 100 nanoparticle formulation, characterization and release kinetics
Öztürk, Ahmet Alper; Yenilmez, Evrim; Yazan, Yasemin (İstanbul Medipol University, 2019)Development and in vitro evaluation of dexketoprofen trometamol (DT)-loaded nanosized and controlled release drug delivery system was aimed in this study. DT-loaded Eudragit® RL 100 polymeric nanoparticles were prepared ... -
Dexketoprofen Trometamol-Loaded Kollidon (R) SR and Eudragit (R) RS 100 Polymeric Nanoparticles: Formulation and In Vitro-In Vivo Evaluation
Öztürk, Ahmet Alper; Yenilmez, Evrim; Arslan, Rana; Şenel, Behiye; Yazan, Yasemin (Colegio Farmaceuticos Provincia De Buenos Aires, 2017)Development and in vivo/in vitro evaluation of dexketoprofen trometamol (DT)-loaded nanosized, controlled release drug delivery system was aimed in this study.. DT-loaded Kollidon (R) SR (KSR) and Eudragit (R) RS 100 (ERS) ... -
Dexketoprofen trometamol-loaded kollidon® SR and eudragit® RS 100 polymeric nanoparticles: Formulation and in vitro-in vivo evaluation
Öztürk, Ahmet Alper; Yenilmez, Evrim; Arslan, Rana; Şenel, Behiye; Yazan, Yasemin (Colegio de Farmaceuticos de la Provincia de Buenos Aires, 2017)Development and in vivo/in vitro evaluation of dexketoprofen trometamol (DT)-loaded nanosized, controlled release drug delivery system was aimed in this study.. DT-loaded Kollidon® SR (KSR) and Eudragit® RS 100 (ERS) ... -
Dexketoprofen trometamol-loaded poly-lactic-co-glycolic acid (PLGA) nanoparticles: Preparation, in vitro characterization and cyctotoxity
Öztürk, Ahmet Alper; Banderas, Lucia Martin; Otero, Maria D. Cayero; Yenilmez, Evrim; Senal, Behiye; Yazan, Yasemin (Pharmacotherapy Group, 2019)Purpose: To design, formulate and characterize sustained-release formulations of dexketoprofen trometamol (DT) nanoparticles (NPs) Methods: Dexketoprofen trometamol (DT)-loaded poly(lactic-co-glycolic acid) (PLGA) NPs were ... -
Effects of Different Derivatives of Eudragit Polymer on Entrapment Efficiency, In Vitro Dissolution, Release Kinetics and Cell Viability Results on Extended Release Flurbiprofen Loaded Nanomedicines
Öztürk, Ahmet Alper; Güven, Umay Merve; Yenilmez, Evrim; Şenel, Behiye (Colegio Farmaceuticos Provincia De Buenos Aires, 2018)The purpose of the present investigation was to design and compare the release characteristics of sustained-release formulations of Flurbiprofen (FLB) loaded nanoparticles (NPs) by using spray-dryer technique using Eudragit ... -
Effects of different derivatives of eudragit polymer on entrapment efficiency, in vitro dissolution, release kinetics and cell viability results on extended release flurbiprofen loaded nanomedicines
Öztürk, Ahmet Alper; Güven, Umay Merve; Yenilmez, Evrim; Şenel, Behiye (Colegio de Farmaceuticos de la Provincia de Buenos Aires, 2018)The purpose of the present investigation was to design and compare the release characteristics of sustained-release formulations of Flurbiprofen (FLB) loaded nanoparticles (NPs) by using spray-dryer technique using Eudragit ... -
Evaluation of carvedilol-loaded Eudragit®nanoparticles
Güven, Umay (2020)The objective of present study was to prepare positively charged carvedilol-loaded nanoparticles providing a controlled release formulationby spray dryer techniqueand wasto examine the effect of different derivative of ... -
Flurbiprofen loaded gel based topical delivery system: Formulation and in vitro characterization with new developed UPLC method
Öztürk, Ahmet Alper; Güven, Umay Merve; Yenilmez, Evrim (İstanbul Medipol University, 2018)Objective: The purpose of this study was to formulate flurbiprofen (FLB) loaded methylcellulose (MC), hydroxypropyl methylcellulose (HPMC) and Carbopol®940 (C-940) based gel formulations with the help of dispersion method ... -
Influence of glyceryl behenate, tripalmitin and stearic acid on the properties of clarithromycin incorporated solid lipid nanoparticles (SLNs): Formulation, characterization, antibacterial activity and cytotoxicity
Öztürk, Ahmet Alper; Aygül, A.; Şenel, B. (Editions de Sante, 2019)Clarithromycin (CLR) is a macrolide derivative which is included in BCS class 2 with low oral bioavailability. Solid lipid nanoparticles (SLNs) have been studied by many researchers for drug application and are very popular ... -
New Approach to Hypertension Treatment: Carvediol-Loaded PLGA Nanoparticles, Preparation, In Vitro Characterization and Gastrointestinal Stability
Öztürk, Ahmet Alper; Martin Banderas, Lucia; Cayero Otero, Maria D.; Yenilmez, Evrim; Yazan, Yasemin (Colegio Farmaceuticos Provincia De Buenos Aires, 2018)Carvedilol (CVL) has advantages over the first generation of beta-blockers in patients with heart failure due to its properties of reducing cardiovascular morbidity and mortality. On the other hand, CVL has a short half-life ... -
New approach to hypertension treatment: Carvediol-loaded PLGA nanoparticles, preparation, in vitro characterization and gastrointestinal stability
Öztürk, Ahmet Alper; Martin, Banderas, L.; Cayero Otero, Maria D.; Yenilmez, Evrim; Yazan, Yasemin (Colegio de Farmaceuticos de la Provincia de Buenos Aires, 2018)Carvedilol (CVL) has advantages over the first generation of ß-blockers in patients with heart failure due to its properties of reducing cardiovascular morbidity and mortality. On the other hand, CVL has a short half-life ... -
Supervised Machine Learning Algorithms for Evaluation of Solid Lipid Nanoparticles and Particle Size
Öztürk, Ahmet Alper; Gündüz, A. Bilge; Özışık, Özan (Bentham Science Publ LTD, 2018)Aims and Objectives: Solid Lipid Nanoparticles (SLNs) are pharmaceutical delivery systems that have advantages such as controlled drug release, long-term stability etc. Particle Size (PS) is one of the important criteria ...
