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Toplam kayıt 691, listelenen: 651-660
Essential oil composition and antimicrobial activity of Glaucosciadium cordifolium (Boiss.) Burtt. & Davis
(Anadolu Üniversitesi, 2022)
Glaucosciadium cordifolium (Boiss.) Burtt. & Davis, which is a monotypic species naturally grown in Turkey belonging to the Apiaceae (Umbelliferae) family. In this study, the essential oil obtained from G. cordifolium was ...
Focusing on the moderately active compound (MAC) in the design and development of strategies to optimize the apoptotic effect by molecular mechanics techniques
(Anadolu Üniversitesi, 2022)
Today, chemotherapeutic agents are mostly used to fight cancer in clinics. But even though they have selectivity for cancer cells, their mechanism of action could result in necrosis. Therefore, we aimed to suggest new ...
Latest research about active pharmaceutical ingredient loaded Poly Lactic Acid-co-Glycolic Acid (PLGA) based drug delivery system in Türkiye
(Anadolu Üniversitesi, 2022)
Some of the most well-engineered and produced biomaterials are polyesters based on polyglycolic acid (PGA), polylactic acid (PLA), and their copolymers, polylactic acid co-glycolic acid (PLGA). In controlled release systems, ...
Synthesis, biological activity evaluation and molecular docking studies of novel thiazole derivatives
(Anadolu Üniversitesi, 2023)
Resistance to existing drugs develops because of insensible use of antibacterial and antifungal drugs. Therefore, there is a need for the development of new drug candidate compounds. The thiazole ring has many biological ...
Determination of potential probiotic properties of lactic acid bacteria isolated from colostrum milk
(Anadolu Üniversitesi, 2023)
Colostrum milk has been used as a source for isolating many probiotic bacteria since it contains many helpful probiotic microorganisms. Because of the huge microorganism diversity and functionality of colostrum, there is ...
The role of immunotherapy in lung cancer: Actual scenery
(Anadolu Üniversitesi, 2023)
More than half of those who succumb to cancer each year also lose their battle with the disease, making cancer a leading cause of death worldwide. After surgery, hormonal therapy, radiotherapy and chemotherapy, which are ...
A new HPLC method for selexipag analysis in pharmaceutical formulation and bulk form
(Anadolu Üniversitesi, 2023)
Selexipag is a new non-prostanoid prostacyclin receptor agonist used to treat pulmonary arterial hypertension. Selexipag is a long-acting IP receptor agonist with a shorter half-life than all other licensed drugs targeting ...
Evaluation of in vitro hepatotoxicity of perampanel in comparison with carbamazepine: old versus new
(Anadolu Üniversitesi, 2023)
Since the liver metabolizes many drugs, including antiepileptics, this organ is the main target of drug-induced damage. There is very little data on hepatotoxicity due to carbamazepine and perampanel metabolized in the ...
Screening of new morpholine dithiocarbamate derivatives bearing benzimidazole moiety for anticholinesterase potential
(Anadolu Üniversitesi, 2023)
Alzheimer’s disease (AD) is basically associated with disturbances of cholinesterase metabolism which result in acetylcholine deficiency. Target of acetylcholinesterase (AChE) inhibitors used in symptomatic therapy of ...
Determination of cytotoxic, antioxidant activities and LC/MS-MS profiles of three endemic Verbascum L. species
(Anadolu Üniversitesi, 2023)
The Verbascum genus includes many species used in folk medicine or the treatment of various diseases. In this study, the cytotoxic, antioxidant activity, and LC/MS-MS profiles of three Verbascum species, which are endemic ...