Browsing Farmasötik Toksikoloji Anabilim Dalı by Title
Now showing items 21-40 of 46
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Estrogenic effects of lycopene and beta-carotene on ER(+) HeLa and LNcaP cancer cells
(Blackwell Publishing, 2006)… -
Evaluation of antimicrobial, Cytotoxic and genotoxic activities of Ganoderma lucidum (Reishi mushroom)
(University Karachi, 2017)Ganoderma lucidum (GL) is a mushroom used as a traditional remedy for the treatment of various infections since ancient times. This study, was aimed to investigate antimicrobial activity potential of GL against Staphylococcus ... -
Evaluation of azithromycin induced cardiotoxicity in rats
(E-Century Publishing Corp, 2015)Although there are possible cardiovascular adverse effects associated with the azithromycin treatment according to some case reports and cohort studies, there is no experimental study evaluating cardiotoxicity in repeated ... -
Evaluation of cardiotoxic effect potential of ciprofloxacin and ofloxacin in juvenile rats using serum biochemical parameters
(Elsevier Ireland LTD, 2007)… -
Evaluation of hepatotoxicity associated with citalopram administration in rats
(Elsevier Ireland LTD, 2015)… -
Evaluation of the reproductive toxicity of levetiracetam in male rats
(Elsevier Ireland LTD, 2016)… -
Evaluation of the reproductive toxicity of naproxen sodium and meloxicam in male rats
(SAGE Publications LTD, 2015)Nonsteroidal anti-inflammatory drugs that are cyclooxygenase (COX) enzyme inhibitors have generally been used in short-term pain management and also to treat inflammation chronically. It is known that COX enzyme and ... -
Evidence for cardiotoxicity associated with sertraline in rats
(Royal Soc Chemistry, 2018)Sertraline is an antidepressant that is frequently prescribed to treat depression, obsessive-compulsive disorder, panic disorder, and anxiety. This drug had a safe cardiotoxicity profile, until the reporting of cases of ... -
Evidence for neurotoxicity associated with amoxicillin in juvenile rats
(SAGE Publications LTD, 2016)Amoxicillin (AMX) is one of the most commonly prescribed antibiotics for children, and childhood is the period to have the highest risk for toxicity cases including drug-induced adverse reactions. Some neurological adverse ... -
Insulin Neuropathy: Rare Adverse Effect of Insulin Therapy
(Ibn Sina Trust, 2016)Insulin neuropathy is a rare adverse effect of insulin therapy in patients with long-term uncontrolled hyperglycemia. Neuropathic pain appears after the correction of blood glucose level. A 34 years old woman with severe ... -
Insulin neuropathy: Rare adverse effect of insulin therapy
(Ibn Sina Trust, 2016)Insulin neuropathy is a rare adverse effect of insulin therapy in patients with long-term uncontrolled hyperglycemia. Neuropathic pain appears after the correction of blood glucose level. A 34 years old woman with severe ... -
Is N-acetyl cysteine protective against monocrotaline-induced toxicity?
(Taylor & Francis Inc, 2013)Monocrotaline (MCT) is a pyrrolizidine alkaloid which induces cardio-pulmonary toxicity and hepatotoxicity in animals and humans. MCT is frequently ingested because of food grain contamination accidentally or in the form ... -
Ketamine: A popular recreational drug: Review [Ketamin: Popüler bir keyif verici i·laç]
(Turkiye Klinikleri, 2005)Ketamine is an anaesthetic agent, characterised by rapid onset of action with profound analgesic and moderate hypnotic properties. Today, the pharmacological use of ketamine is limited. However, because of its hallucinogenic ... -
Matrix metalloproteinases are possible targets in monocrotaline-induced pulmonary hypertension: investigation of anti-remodeling effects of alagebrium and everolimus
(Turkish Soc Cardiology, 2017)Objective: In our study, sildenafil alone and everolimus or alagebrium in combination with sildenafil were investigated in terms of their additional therapeutic and anti-remodeling activity in monocrotaline-induced pulmonary ... -
Novel Benzylidene Thiazolidinedione Derivatives as Partial PPAR gamma Agonists and their Antidiabetic Effects on Type 2 Diabetes
(Nature Publishing Group, 2017)Peroxisome proliferator-activated receptor gamma (PPAR gamma) has received significant attention as a key regulator of glucose and lipid homeostasis. In this study, we synthesized and tested a library of novel 5-benzylid ... -
Oxidative stress-mediated myrocardiotoxicity of ciprofloxacin and ofloxacin in juvenile rats
(Taylor & Francis Inc, 2009)In this study, evaluation of the myocardiotoxic effect potential of ciprofloxacin and ofloxacin in juvenile rats and the role of oxidative stress in heart toxicity was conducted. Doses (25 and 50 mg/kg) of each drug were ... -
Reproductive toxic effects and possible mechanisms of zonisamide in male rats
(SAGE Publications Ltd, 2019)Zonisamide (ZNS) is an anticonvulsant which is used to treat the symptoms of epilepsy. Although it is frequently used during reproductive ages, studies that investigated the effects of ZNS on reproductive system are limited. ... -
Reproductive toxicity after levetiracetam administration in male rats: Evidence for role of hormonal status and oxidative stress
(Public Library Science, 2017)Levetiracetam (LEV) is an antiepileptic drug commonly used in the treatment of epilepsy because of its excellent safety profile in all age groups. It is remarkable that there are no studies evaluating the toxic effects of ...