Başlık için Farmasötik Toksikoloji Anabilim Dalı listeleme

Acute and Subchronic Toxic Effects of the Fruits of Physalis peruviana L.

Perk, Başak Özlem; Ilgın, Sinem; Atlı Eklioğlu, Özlem; Duymuş, Hale Gamze; Sırmagül, Başar (Hindawi Publishing Corporation, 2013)

The fruit of Physalis peruviana L. (PPL) has been traditionally used as antispasmodic, diuretic, antiseptic, sedative, and analgesic all over the world. We aimed to perform qualitative content analysis of the fruits of PPL ...

Acute drug poisonings in Eskisehir, Turkey: A retrospective study

Ergün, Bülent; Çevik, Alper Arif; Ilgın, Sinem; Atlı Eklioğlu, Özlem; Saraçoğlu, Ahmet; Acar, Nurdan (2013)

Bu çalışmada ESOGU Tıp Fakültesi Hastanesi Yetişkin Acil Servisine Ocak 2003 - Aralık 2009 yılları arasında başvuran akut ilaç zehirlenme olgularının retrospektif olarak değerlendirilmesi amaçlanmaktadır. Bu amaçla olgulara ...

Acute drug poisonings in Eskisehir, Turkey: A retrospective study [Eskişehirde akut i·laç zehirlenmeleri: Retrospektif bir çahşma]

Ergün, Bülent; Çevik, Alper Arif; Ilgın, Sinem; Atlı Eklioğlu, Özlem; Saraçoğlu, Ahmet; Acar, N.; Uzuncakara, D. (2013)

The aim of this study was to characterize acute drug-poisoning cases admitted to the Adult Emergency Service of ESOGU Medicine Faculty Hospital, Turkey. All acute drug-poisoning cases admitted to the emergency service from ...

Assessment of the Endothelial Functions in Monocrotaline-induced Pulmonary Hypertension

Sırmagül, Başar; Ilgın, Sinem; Atlı Eklioğlu, Özlem; Usanmaz, Suzan Emel; Demirel-Yılmaz, Emine (Taylor & Francis Inc, 2013)

Pulmonary hypertension (PH) is a life-threatening disease that causes endothelial dysfunction in the pulmonary vascular bed. Systemic endothelial dysfunction has also been reported in PH. This study compared the systemic ...

Assessment of the potential reproductive toxicity of citalopram in male rats

Atlı Eklioğlu, Özlem; Baysal, Merve; Kılıç, G.; Kılıç, Volkan; Uçarcan, Şeyda; Korkut, B.; Ilgın, Sinem (Elsevier Ireland LTD, 2016)

…

Assessment of trazodone-induced cardiotoxicity after repeated doses in rats

Atlı Eklioğlu, Özlem; Kılıç, Volkan; Baysal, Merve; Aydoğan Kılıç, Gözde; Gormus, G.; Ucarcan, S.; Ilgın, Sinem (SAGE Publications LTD, 2019)

Trazodone (TRZ) is an antidepressant drug commonly used in the treatment of depression, anxiety, and insomnia. Although some studies demonstrated the adverse effects of TRZ related to cardiovascular system, the conflicting ...

Biotransformation of abietic acid by fungi and biological evaluation of its metabolites

Özşen, Özge; Kıran, İsmail; Dağ, İlknur; Atlı Eklioğlu, Özlem; Çiftçi, Gülsen Akalın; Demirci, Fatih (Elsevier Sci LTD, 2017)

Biotransformation of abietic acid was carried out initially using 28 different microbial strains. Among the evaluated, Mucor ramannianus produced a known metabolite namely 2 alpha-hydroxy-dehydroabietic acid whereas ...

Cardioprotection with resveratrol pretreatment: improved beneficial effects over standard treatment in rat hearts after global ischemia

Dernek, S; İkizler, M; Erkasap, Nilüfer; Ergün, B; Köken, T; Yılmaz, K; Kural, T (Taylor & Francis LTD, 2004)

Objective-The major objective of the present study is to evaluate the potential role of resveratrol (RVT), a natural antioxidant found in grapes and red wine, in protecting the myocardium from the deleterious effects of ...

Ciprofloxacin-induced neurotoxicity: evaluation of possible underlying mechanisms

Ilgın, Sinem; Can, Özgür Devrim; Atlı Eklioğlu, Özlem; Ucel, Umut İrfan; Şener, Erol; Güven, İlkay (Taylor & Francis LTD, 2015)

Ciprofloxacin (CPX) is a fluoroquinolone antibiotic used for treating respiratory, urinary tract, gastrointestinal and abdominal infections. There are only a limited number of studies related to neurological adverse effects ...

Citalopram Induces Reproductive Toxicity in Male Rats

Ilgın, Sinem; Aydoğan-Kılıc, G.; Baysal, Merve; Kılıç, Volkan; Korkut, Büşra; Uçarcan, Şeyda; Atlı Eklioğlu, Özlem (Wiley, 2017)

Background: Citalopram hydrobromide (CTL) has been shown to cause sexual dysfunction; however, its reproductive toxicity potential has not been sufficiently elucidated in men. Therefore, we aimed to clarify the toxic effects ...

Composition of some herbal slimming tea preparations marketed in Turkey and their possible adverse effects [Türkiye'de satilan bazi bitkisel zayiflama çaylarinin i·çerikleri ve bu çaylarin kullanimina bagli ortaya çikabilecek i·stenmeyen etkiler]

Saraçoğlu, Ahmet; Ergün, Bülent (Turkiye Klinikleri, 2006)

Objective: The interest in herbal products has been increasing in recent years. Herbal weight-loss products are widely used because they are believed to be harmless, especially among women who want to lose weight. However, ...

Consideration of anticarcinogenic activity of lycopene on ER(+) HeLa and LNCaP cancer cells

Ilgın, Sinem; Ergün, Bülent (Elsevier Ireland LTD, 2007)

…

Design and Synthesis of New Benzothiazole Compounds as Selective hMAO-B Inhibitors

Ilgın, Sinem; Osmaniye, Derya; Levent, Serkan; Sağlık, Begüm Nurpelin; Çevik, Ulviye Acar; Kaya Çavuşoğlu, Betül; Kaplancıklı, Zafer Asım (MDPI AG, 2017)

In the current work a new class of novel benzothiazole-hydrazone derivatives was designed and synthesized as hMAO-B inhibitors. Structures of the obtained compounds (3a-3j) were characterized by IR, 1H-NMR, 13C-NMR, and ...

Determination of hesperidin and neohesperidin in fruit juices using high performance liquid chromatographic (HPLC) method

Atlı Eklioğlu, Özlem; Ergün, Bfilent; Altıokka, Göksel (Elsevier Ireland LTD, 2007)

…

Determination of Phenolic Compounds of Stachys Rupestris Montbret Et Aucher Ex Bentham By Lc-Ms/Ms and Its Biological Activities

Ergün, Bülent; Göğer, Fatih; Köse, Yavuz Bülent; İşcan, Gökalp (Parlar Scientific Publications (PSP), 2018)

One of the largest genus of Lamiaceae, Stachys, extended from south western part of Asia to America, represented in Turkey with % 48 endemism rate. In this presented study LC-ESI-MS/MS properties, anticandidal, antioxidant ...