Ara
Toplam kayıt 37, listelenen: 11-20
Biotransformation of abietic acid by fungi and biological evaluation of its metabolites
(Elsevier Sci LTD, 2017)
Biotransformation of abietic acid was carried out initially using 28 different microbial strains. Among the evaluated, Mucor ramannianus produced a known metabolite namely 2 alpha-hydroxy-dehydroabietic acid whereas ...
Evaluation of the reproductive toxicity of naproxen sodium and meloxicam in male rats
(SAGE Publications LTD, 2015)
Nonsteroidal anti-inflammatory drugs that are cyclooxygenase (COX) enzyme inhibitors have generally been used in short-term pain management and also to treat inflammation chronically. It is known that COX enzyme and ...
Determination of hesperidin and neohesperidin in fruit juices using high performance liquid chromatographic (HPLC) method
(Elsevier Ireland LTD, 2007)
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Reproductive toxic effects and possible mechanisms of zonisamide in male rats
(SAGE Publications Ltd, 2019)
Zonisamide (ZNS) is an anticonvulsant which is used to treat the symptoms of epilepsy. Although it is frequently used during reproductive ages, studies that investigated the effects of ZNS on reproductive system are limited. ...
Evidence for cardiotoxicity associated with sertraline in rats
(Royal Soc Chemistry, 2018)
Sertraline is an antidepressant that is frequently prescribed to treat depression, obsessive-compulsive disorder, panic disorder, and anxiety. This drug had a safe cardiotoxicity profile, until the reporting of cases of ...
Oxidative stress-mediated myrocardiotoxicity of ciprofloxacin and ofloxacin in juvenile rats
(Taylor & Francis Inc, 2009)
In this study, evaluation of the myocardiotoxic effect potential of ciprofloxacin and ofloxacin in juvenile rats and the role of oxidative stress in heart toxicity was conducted. Doses (25 and 50 mg/kg) of each drug were ...
Is N-acetyl cysteine protective against monocrotaline-induced toxicity?
(Taylor & Francis Inc, 2013)
Monocrotaline (MCT) is a pyrrolizidine alkaloid which induces cardio-pulmonary toxicity and hepatotoxicity in animals and humans. MCT is frequently ingested because of food grain contamination accidentally or in the form ...
Toxic Effects of Trazodone on Male Reproductive System via Disrupting Hypothalamic-Pituitary-Testicular Axis and Inducing Testicular Oxidative Stress
(Hindawi LTD, 2018)
Depression and anxiety are recognized as public health problems. Epidemiological studies have shown that depression and anxiety often occur during reproductive ages between 20 and 60 years of age in males. Trazodone is one ...
Novel Benzylidene Thiazolidinedione Derivatives as Partial PPAR gamma Agonists and their Antidiabetic Effects on Type 2 Diabetes
(Nature Publishing Group, 2017)
Peroxisome proliferator-activated receptor gamma (PPAR gamma) has received significant attention as a key regulator of glucose and lipid homeostasis. In this study, we synthesized and tested a library of novel 5-benzylid ...
Matrix metalloproteinases are possible targets in monocrotaline-induced pulmonary hypertension: investigation of anti-remodeling effects of alagebrium and everolimus
(Turkish Soc Cardiology, 2017)
Objective: In our study, sildenafil alone and everolimus or alagebrium in combination with sildenafil were investigated in terms of their additional therapeutic and anti-remodeling activity in monocrotaline-induced pulmonary ...