Kurum Yazarı "Yurttaş, Leyla" Anadolu Üniversitesi Yayınları İçin Listeleme
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Focusing on the moderately active compound (MAC) in the design and development of strategies to optimize the apoptotic effect by molecular mechanics techniques
Evren, Asaf Evrim; Nuha, Demokrat; Yuttaş, Leyla (Anadolu Üniversitesi, 2022)Today, chemotherapeutic agents are mostly used to fight cancer in clinics. But even though they have selectivity for cancer cells, their mechanism of action could result in necrosis. Therefore, we aimed to suggest new ... -
Screening of new morpholine dithiocarbamate derivatives bearing benzimidazole moiety for anticholinesterase potential
Anadolu Üniversitesi; 0000-0002-5233-1165; 0000-0001-9535-2508; 0000-0002-0957-6044; Temel, Halide Edip; Akalın Çiftçi, Gülşen; Yurttaş, Leyla (Anadolu Üniversitesi, 2023)Alzheimer’s disease (AD) is basically associated with disturbances of cholinesterase metabolism which result in acetylcholine deficiency. Target of acetylcholinesterase (AChE) inhibitors used in symptomatic therapy of ... -
Synthesis and in silico evaluation of some new 2,4-disubstituted thiazole derivatives
Anadolu Üniversitesi, Eczacılık Fakültesi; Yurttaş, Leyla; Evren, Asaf Evrim; Özkay, Yusuf (Anadolu Üniversitesi, 2022)The synthesis and anti-proliferative activity investigation of methyl 3/4-[[4-(2-substituted thiazol-4-yl)phenyl]amino]-3-oxopropanoate/(4-oxobutanoate) (3a-h) derivatives were aimed in this work. The synthesis of the new ...