Kurum Yazarı "Çelik, İlhami" Fen Fakültesi İçin Listeleme
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Antibacterial activities of the methanol extract, fractions and compounds from Elaeophorbia drupifera (Thonn.) Stapf. (Euphorbiaceae)
Voukeng, Igor K.; Nganou, Blaise K.; Sandjo, Louis P.; Çelik, İlhami; Beng, Veronique P.; Tane, Pierre; Kuete, Victor (Biomed Central LTD, 2017)Background: Elaeophorbia drupifera (Thonn.) Stapf. (Euphorbiaceae) is used in Cameroonian folk medicine to treat several ailments including bacterial-related diseases such as skin infections. In this study, the methanol ... -
Antibacterial activities of the methanol extracts, fractions and compounds from Harungana madagascariensis Lam. ex Poir. (Hypericaceae)
Tankeo, Simplice B.; Damen, Francois; Sandjo, Louis P.; Çelik, İlhami; Tane, Pierre; Kuete, Victor (Elsevier Ireland LTD, 2016)Ethnopharmacological relevance: Harungana madagascariensis Lam. ex Poir. (Hypericaceae) is used in folk medicine to treat a variety of human ailments, mainly antibacterial, antifungal, antiviral and viral infections. In ... -
Benzotriazole-mediated amidoalkylations of nitroalkanes, nitriles, alkynes and esters
Katritzky, Alan R.; Abdel-Fattah, Ashraf A. A.; Çelik, İlhami (Arkat Usa Inc, 2007)Reactions of readily available and stable N-(alpha-amidoalkyl)benzotriazoles 1 ( derived from a variety of aliphatic, aromatic or heterocyclic aldehydes) with diverse nitroalkanes, nitriles, alkynes and esters afforded ... -
Convenient synthesis of C-terminal di- and tri-peptide amides from N-protected dipeptidoylbenzotriazoles
Çelik, İlhami; Abdel-Fattah, Ashraf A. A. (Pergamon-Elsevier Science LTD, 2009)N-Protected dipeptidoylbeiizotriazoles react with aqueous ammonia to give dipeptide primary amides (77-98%) and with N-unprotected alpha-amino amides to afford tripeptide primary amides (82-86%). -
In vitro antibacterial and antibiotic modifying activity of crude extract, fractions and 3 ', 4 ', 7-trihydroxyflavone from Myristica fragrans Houtt against MDR Gram-negative enteric bacteria
Dzotam, Joachim K.; Simo, Ingrid Konga; Bitchagno, Gabin; Çelik, İlhami; Sandjo, Louis P.; Tane, Pierre; Kuete, Victor (Biomed Central LTD, 2018)Background: Nutmeg is the seed kernel inside the fruit of Myristica fragrans Houtt. (Myristicaceae). It possesses various pharmacological activities but is used in Cameroon only for its flavor in making cakes. The present ... -
N-(2-Aminobenzoyl)benzotriazole mediated and t-BuOK promoted synthesis of 2-substituted quinolone 3-carboxylates
Kökten, Şule; Çelik, İlhami (Pergamon-Elsevier Science LTD, 2015)2-Substituted quinolone 3-carboxylates were obtained in moderate to good yields by the reaction of N-(2-aminobenzoyl)benzotriazoles with beta-ketoesters in the presence of t-BuOK in THF -
N-(alpha-Amidoalkyl)benzotriazole-mediated synthesis of beta '-amido beta-diketones: a general synthetic protocol for N-[beta-(3,5-di and 1,3,5-trisubstituted pyrazol-4-yl)alkyl] amides
Çelik, İlhami; Kanışkan, Nevin; Kökten, Şule (Pergamon-Elsevier Science LTD, 2009)Various beta '-amido-beta-diketones were first synthesized with N-(alpha-amidoalkyl)benzotriazole-mediated amidoalkylation of 1,3-diketones in moderate yields. These intermediates undergo rapid condensation with hydrazines ... -
A naturally occuring triterpene saponin ardisiacrispin B displayed cytotoxic effects in multi-factorial drug resistant cancer cells via ferroptotic and apoptotic cell death
Mbaveng, Armelle T.; Ndontsa, Blanche L.; Kuete, Victor; Nguekeu, Yves M. M.; Çelik, İlhami; Mbouangouere, Roukayatou; Efferth, Thomas (Elsevier GMBH, Urban & Fischer Verlag, 2018)Introduction: Multidrug resistance of cancer cells constitutes a serious problem in chemotherapy and a challenging issue in the discovery of new cytotoxic drugs. Many saponins are known to display anti-cancer effects. In ... -
A new protocol for the synthesis of primary, secondary and tertiary anthranilamides utilizing N-(2-aminoarylacyl)benzotriazoles
Kaniskan, Nevin; Kökten, Şule; Çelik, İlhami (Arkat Usa Inc, 2012)A convenient route for efficient conversion of unprotected anthranilic acids into the corresponding N-(2-aminoarylacyl)benzotrazoles is described. N-(2-Aminoarylacyl)benzotrazoles have been successfully used to synthesize ... -
One-step potentiostatic codeposition and electrochemical studies of poly(1-pyrenyl)-2,5-di(2-thienyl)pyrrole-co-pyrrole) film for electrochemical supercapacitors
Görçay, Hakan; Çelik, İlhami; Şahin, Yücel (Scientific Technical Research Council Turkey-Tubitak, 2018)In this paper, we report a simple, low-cost, and environmentally friendly electrochemical method to obtain a novel copolymer consisting of l-pyrenyl-2,5-di(2-thienyl)pyrrole and pyrrole on a pencil graphite electrode (PGE). ... -
A Simple, Mild, and Practical Method for the Esterification and Thioesterification of Anthranilic Acid Utilizing N-(2-Aminobenzoyl)benzotriazole
Kökten, Şule; Çelik, İlhami (Georg Thieme Verlag Kg, 2013)A convenient and efficient method for the preparation of anthranilic esters and anthranilic thioesters has been developed by the treatment of N-(2-aminobenzoyl)benzotriazoles with alcohols and thiols in the presence of ... -
Stereoselective and regioselective synthesis of N-substituted methyl 2-((azolyl)methyl)-3-arylacrylates from Baylis-Hillman acetates
Özenç, Köseceli Ayşen; Çelik, İlhami; Kökten, Şule (Scientific Technical Research Council Turkey-Tubitak, 2017)N-Substituted methyl 2-((azolyl)methyl)-3-arylacrylates were synthesized stereo- and regioselectively with one-pot reaction between Baylis-Hillman acetates and a suitable acylazole in the presence of K2CO3 as a base catalyst. ... -
Stereoselective and regioselective synthesis of NN-substituted methyl 2-((azolyl)methyl)-3-arylacrylates from Baylis-Hillman acetates
N -Substituted methyl 2-((azolyl)methyl)-3-arylacrylates were synthesized stereo- and regioselectively with one-pot reaction between Baylis–Hillman acetates and a suitable acylazole in the presence of K2 CO3 as a base ... -
Synthesis of 4-hydroxyquinoline-2,3-dicarboxylates using N-(2-aminobenzoyl)benzotriazoles
Çelik, İlhami; Yıldız, Fatos (Pergamon-Elsevier Science LTD, 2017)A method for the preparation of 4-hydroxyquinoline-2,3-dicarboxylates has been developed by aza-Michael addition reaction of N-(2-aminobenzoyl)benzotriazoles with dimethyl acetylenedicarboxylate. 4-Hydroxyquinoline-2,3-d ... -
Thioamidoalkylation of 1,3-dicarbonyl compounds, enol silyl ethers, and enamines
Katritzky, Alan R.; Çelik, İlhami; Abdel-Fattah, Ashraf A. A. (Georg Thieme Verlag Kg, 2007)Novel syntheses of beta-thioamido ketones via thioamidoalkylations of malonates, beta-keto esters, beta-diketones, enol silyl ethers, and enamines with N-(alpha-thioamidoalkyl)benzotriazoles are described.